Find coaches from Pittsburgh to Knoxville, TN

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Today21 Jun
Tomorrow22 Jun
from US$107
Mon23 Jun
from US$96
Tue24 Jun
Wed25 Jun
from US$97
Thu26 Jun
from US$122
Fri27 Jun
Sat28 Jun

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 22 June at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: 22 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 22 June at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: 23 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Pittsburgh to Knoxville: Trip Overview

Average ticket priceUS$116
Average bus trip duration21h 30m
Number of daily buses1.9
Earliest bus departure01:35
Distance372 miles
Latest bus departure20:35

Pittsburgh to Knoxville Bus

With Busbud, comparing and booking tickets for a bus from Pittsburgh to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Pittsburgh to Knoxville will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Pittsburgh to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Pittsburgh - Knoxville, TN

  1. How far is Knoxville from Pittsburgh by coach?

    The distance between Pittsburgh and Knoxville by coach is approximately 376 miles (606 km).

  2. What is the best way to go from Pittsburgh to Knoxville without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
19/06
US$93
20/06
US$90
Today
US$97
22/06
US$99
23/06
US$88
24/06
No data
25/06
US$89
26/06
US$114
busbud logoThe cheapest trip from Pittsburgh to Knoxville was searched and found on 23 Jun 2025 with a price of US$88

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Knoxville as early as possible.

You can expect to pay from US$88 to US$121 for a bus ticket from Pittsburgh to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at US$88, which is on 2025-06-23.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Pittsburgh to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Pittsburgh to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Pittsburgh to Knoxville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Pittsburgh to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Pittsburgh by bus?

Bus from Pittsburgh to Knoxville

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