Find coaches from Knoxville, TN to Pittsburgh

Find affordable coach tickets from Knoxville, TN to Pittsburgh with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen journeys

One passenger / one way

  • Departure time: 5 September at
    Departure city: Knoxville
    Departure location: Knoxville Bus Station
    Arrival time: 7 September at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 11 October at
    Departure city: Knoxville
    Departure location: Knoxville Bus Station
    Arrival time: 12 October at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 18 October at
    Departure city: Knoxville
    Departure location: Knoxville Bus Station
    Arrival time: 19 October at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 18 October at
    Departure city: Knoxville
    Departure location: Knoxville Bus Station
    Arrival time: 19 October at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 18 October at
    Departure city: Knoxville
    Departure location: Knoxville Bus Station
    Arrival time: 20 October at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Knoxville, TN to Pittsburgh: Trip Overview

Average ticket priceUS$114
Average bus trip duration20h
Number of daily buses1
Earliest bus departure18:15
Distance372 miles
Latest bus departure22:50

Knoxville to Pittsburgh Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Pittsburgh.

We make sure you can find a bus service from Knoxville to Pittsburgh from the most reliable bus companies operating this trip.

Discover how much the bus trip from Knoxville to Pittsburgh will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Knoxville, TN - Pittsburgh

  1. How much does a bus ticket from Knoxville to Pittsburgh cost?

    The bus ticket price from Knoxville to Pittsburgh starts at US$81. The best way to find cheap bus tickets from Knoxville to Pittsburgh is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Knoxville to Pittsburgh?

    The average travel time between Knoxville and Pittsburgh is around 20h, although the fastest bus will take about 20h. This is the time it takes to travel the 376 miles that separates the two cities.

  3. How many daily bus connections are there between Knoxville and Pittsburgh?

    The number of buses from Knoxville to Pittsburgh can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Knoxville to Pittsburgh by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Knoxville to Pittsburgh?

    When taking the bus from Knoxville to Pittsburgh, you can travel comfortably and safely with Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/08
US$124
30/08
US$92
Today
US$122
01/09
No data
02/09
No data
03/09
No data
04/09
No data
05/09
No data
busbud logoThe cheapest trip from Knoxville, TN to Pittsburgh was searched and found on 30 Aug 2025 with a price of US$92

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Pittsburgh as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Pittsburgh but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Knoxville to Pittsburgh, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Knoxville to Pittsburgh will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Pittsburgh.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Knoxville, TN by bus?

Bus from Pittsburgh to Knoxville, TN

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Knoxville

Buses Leaving from Knoxville

Buses Going to Knoxville

Popular Buses Connecting Pittsburgh

Buses Leaving from Pittsburgh

Buses Going to Pittsburgh