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- This trip is recommended because it is: Cheapest + FastestDeparture time: June 22 atDeparture city: PittsburghDeparture location: Pittsburgh Intermodal StationArrival time: June 22 atDestination city: KnoxvilleDestination location: Knoxville Bus StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: June 22 atDeparture city: PittsburghDeparture location: Pittsburgh Intermodal StationArrival time: June 23 atDestination city: KnoxvilleDestination location: Knoxville Bus StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
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Bus Pittsburgh to Knoxville: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Pittsburgh to Knoxville Bus
With Busbud, comparing and booking tickets for a bus from Pittsburgh to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Pittsburgh to Knoxville will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Pittsburgh to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Pittsburgh and Knoxville?
Frequently asked questions for your trip Pittsburgh - Knoxville, TN
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Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to Knoxville was searched and found on Jun 23, 2025 with a price of $88To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Knoxville, as early as possible.
You can expect to pay from $88 to $121 for a bus ticket from Pittsburgh to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at $88 which is on 2025-06-23.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Pittsburgh to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Pittsburgh to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Pittsburgh to Knoxville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Pittsburgh to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Buses Going to Knoxville
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