Find coaches from New Orleans to Knoxville, TN

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Today2 Sept
Tomorrow3 Sept
Thu4 Sept
Fri5 Sept
Sat6 Sept
Sun7 Sept
from US$104
Mon8 Sept
Tue9 Sept

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 7 September at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: 8 September at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 7 September at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: 8 September at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus New Orleans to Knoxville, TN: Trip Overview

Average ticket priceUS$118
Average bus trip duration21h 35m
Number of daily buses2
Earliest bus departure08:20
Distance550 miles
Latest bus departure23:15

New Orleans to Knoxville Bus

Busbud helps you find a bus from New Orleans to Knoxville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from New Orleans to Knoxville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from New Orleans, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip New Orleans - Knoxville, TN

  1. What's the distance between New Orleans and Knoxville by coach?

    The journey from New Orleans to Knoxville by coach covers an approximate distance of 547 miles (882 km).

  2. How can I travel from New Orleans to Knoxville avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/08
US$111
01/09
No data
Today
No data
03/09
No data
04/09
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05/09
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06/09
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07/09
US$111
busbud logoThe cheapest trip from New Orleans to Knoxville, TN was searched and found on 31 Aug 2025 with a price of US$111

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Knoxville, TN as early as possible.

You can expect to pay from US$111 to US$111 for a bus ticket from New Orleans to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at US$111, which is on 2025-09-07.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between New Orleans and Knoxville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New Orleans to Knoxville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from New Orleans to Knoxville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from New Orleans to Knoxville.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to New Orleans by bus?

Bus from Knoxville, TN to New Orleans

Why choose Busbud?

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