Bus Tickets from New Orleans to Knoxville, TN

Next departures

Next departures for New Orleans to Knoxville on September 7
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
New Orleans Bus Station
Knoxville Bus StationCheapestFastest
Greyhound Lines, Inc.
New Orleans Bus Station
Knoxville Bus StationNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus New Orleans to Knoxville, TN: Trip Overview

Average Ticket PriceUS$118
Average Bus Trip Duration21h 35m
Number of daily buses2
Earliest bus departure8:20am
Distance887 km
Latest bus departure11:15pm

New Orleans to Knoxville Bus

Busbud helps you find a bus from New Orleans to Knoxville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from New Orleans to Knoxville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from New Orleans, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip New Orleans - Knoxville, TN

  1. How far is New Orleans from Knoxville?

    It's about 882 km (547 miles) from New Orleans to Knoxville.

  2. What are the departure and arrival locations for buses traveling from New Orleans to Knoxville?

    Buses departing from Union Passenger Terminal in New Orleans will take you to 100 Kirkwood St in Knoxville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-30
No data
08-31
US$111
Today
No data
09-02
No data
09-03
No data
09-04
No data
09-05
No data
09-06
No data
busbud logoThe cheapest trip from New Orleans to Knoxville, TN was searched and found on Aug 31, 2025 with a price of US$111

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Knoxville, TN, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between New Orleans and Knoxville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New Orleans to Knoxville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from New Orleans to Knoxville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from New Orleans to Knoxville.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to New Orleans by bus?

Bus from Knoxville, TN to New Orleans

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting New Orleans

Buses Leaving from New Orleans

Buses Going to New Orleans

Popular Buses Connecting Knoxville

Buses Leaving from Knoxville

Buses Going to Knoxville