Bus Tickets from Orlando to Knoxville, TN

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TodayJun 22
TomorrowJun 23
TueJun 24
from US$160
WedJun 25
from US$135
ThuJun 26
from US$145
FriJun 27
from US$105
SatJun 28
from US$157
SunJun 29

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 24 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 24 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 25 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 25 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Tuesday at 1:03 AM EDT.

Prices and availability are subject to change.

Accepted payments

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  • China Union Pay
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Bus Orlando to Knoxville: Trip Overview

Average Ticket PriceUS$120
Average Bus Trip Duration1d
Number of daily buses3.083333333333334
Earliest bus departure5:15am
Distance860 km
Latest bus departure10:40pm

Orlando to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Orlando to Knoxville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Orlando to Knoxville.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Orlando, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Orlando - Knoxville, TN

  1. How far is Orlando from Knoxville?

    It's about 861 km (534 miles) from Orlando to Knoxville.

  2. What are the departure and arrival locations for buses traveling from Orlando to Knoxville?

    Buses departing from Orlando Bus Station in Orlando will take you to 100 Kirkwood St in Knoxville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-20
No data
06-21
No data
Today
No data
06-23
US$122
06-24
US$152
06-25
US$134
06-26
No data
06-27
No data
busbud logoThe cheapest trip from Orlando to Knoxville was searched and found on Jun 23, 2025 with a price of US$122

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Knoxville, as early as possible.

You can expect to pay from US$122 to US$152 for a bus ticket from Orlando to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at US$122 which is on 2025-06-23.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Orlando to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Orlando to Knoxville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Orlando to Knoxville.

Make a music playlist for your bus ride from Orlando to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Orlando by bus?

Bus from Orlando to Knoxville

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