Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Indianapolis Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Indianapolis Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Indianapolis Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Indianapolis Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Indianapolis Bus Station | Knoxville Bus Station | No tags |
Get from Indianapolis to Knoxville
The journey takes about 10 hours 20 minutes, and with fares starting at just $106, it presents an excellent value for a comfortable ride.
Where are the popular stops in Indianapolis and Knoxville?
Stops in Indianapolis
- A350 S Illinois St, Indianapolis, IN 46225
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87504 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $106
Frequently asked questions about travelling from Indianapolis to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Indianapolis to Knoxville?
The cheapest bus tickets from Indianapolis to Knoxville start from $106. The average price for this route is around $168. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Indianapolis to Knoxville?
The average bus travel time from Indianapolis to Knoxville is 10h 20m, covering a distance of 464 km. The quickest bus can get you there in 9h 45m and is operated by Greyhound.
Which bus companies service the Indianapolis to Knoxville route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Indianapolis to Knoxville?
The earliest bus departs from Indianapolis to Knoxville at 9:10am. And the latest bus departs at 11:25am.
What are the CO₂ emissions for the bus trip from Indianapolis to Knoxville?
A bus trip from Indianapolis to Knoxville generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Knoxville, TN was searched and found on Jan 15, 2026 with a price of $99To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Knoxville, TN, as early as possible.
You can expect to pay from $99 to $183 for a bus ticket from Indianapolis to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $166 which is on 2026-01-17.
