Find coaches from Roanoke to Knoxville, TN

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Previously seen journeys

One passenger / one way

  • Departure time: 20 October at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: 20 October at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 26 October at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: 26 October at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 14 November at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: 14 November at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 20 November at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: 20 November at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 15 December at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: 15 December at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Roanoke to Knoxville, TN: Trip Overview

Average ticket priceUS$48
Average bus trip duration5h 15m
Number of daily buses1
Earliest bus departure12:50
Distance235 miles

Roanoke to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Roanoke to Knoxville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Roanoke to Knoxville.

From cheap bus tickets to more luxurious buses travelling from Roanoke to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Roanoke - Knoxville, TN

  1. How far is Knoxville from Roanoke by coach?

    The distance between Roanoke and Knoxville by coach is approximately 239 miles (385 km).

  2. Is there a way to reach Knoxville from Roanoke without a car?

    You can travel to Knoxville from Roanoke by coach, which provides a smooth ride and an affordable and convenient trip. Depending on your preferences, carpooling can also be considered as an option.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/08
No data
01/09
US$49
Today
US$44
03/09
No data
04/09
US$38
05/09
No data
06/09
No data
07/09
No data
busbud logoThe cheapest trip from Roanoke to Knoxville, TN was searched and found on 4 Sept 2025 with a price of US$38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Knoxville, TN as early as possible.

You can expect to pay from US$38 to US$49 for a bus ticket from Roanoke to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at US$38, which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Roanoke to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Roanoke to Knoxville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Roanoke to Knoxville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Roanoke to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Roanoke by bus?

Bus from Knoxville, TN to Roanoke

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