Find coaches from Iowa City to St. Louis

Next departures

Next departures from Iowa City to St. Louis on 24 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Iowa City
Gateway StationCheapestFastest

Last refresh of the prices: Last Wednesday at 08:39 CDT.

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Bus Iowa City to St. Louis: Trip Overview

Average ticket priceUS$105
Average bus trip duration15h 20m
Number of daily buses1
Earliest bus departure07:50
Distance221 miles
Latest bus departure09:55

Iowa City to St. Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Iowa City to St. Louis.

Bus service from Iowa City to St. Louis will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Iowa City to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Iowa City - St. Louis

  1. What's the distance between Iowa City and St. Louis by coach?

    The distance between Iowa City and St. Louis by coach is approximately 221 miles (357 km).

  2. How can I get from Iowa City to St. Louis without driving?

    You can travel to St. Louis from Iowa City by coach, which provides a smooth ride and an affordable and convenient trip. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
21/09
No data
22/09
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Today
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24/09
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25/09
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26/09
US$86
27/09
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28/09
No data
busbud logoThe cheapest trip from Iowa City to St. Louis was searched and found on 26 Sept 2025 with a price of US$86

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Iowa City to St. Louis as early as possible.

You can expect to pay from US$86 to US$86 for a bus ticket from Iowa City to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$86, which is on 2025-09-26.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Iowa City to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Iowa City to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Iowa City to St. Louis that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Iowa City to St. Louis.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Iowa City by bus?

Bus from St. Louis to Iowa City

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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