Find coaches from Des Moines to St. Louis

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Today6 Sept
Tomorrow7 Sept
Mon8 Sept
from US$66
Tue9 Sept
Wed10 Sept
Thu11 Sept
from US$82
Fri12 Sept
from US$78
Sat13 Sept
from US$83

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 8 September at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: 8 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus Des Moines to St. Louis: Trip Overview

Average ticket priceUS$83
Average bus trip duration17h 35m
Number of daily buses1
Earliest bus departure05:30
Distance273 miles
Latest bus departure08:15

Des Moines to St. Louis Bus

Busbud helps you find a bus from Des Moines to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to St. Louis.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Des Moines, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Des Moines - St. Louis

  1. What's the distance between Des Moines and St. Louis by coach?

    The distance between Des Moines and St. Louis by coach is approximately 273 miles (441 km).

  2. What is the best way to go from Des Moines to St. Louis without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and St. Louis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Des Moines to St. Louis.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Des Moines to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Des Moines by bus?

Bus from St. Louis to Des Moines

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