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- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
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Compare 2 ways to travel from Chicago to St. Louis
Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 5 hours 1 minute and with fares starting at just US$30, it presents an excellent value for a comfortable ride.
Bus Chicago to St. Louis: Trip Overview
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Chicago to St. Louis Bus
With Busbud, comparing and booking tickets for a bus from Chicago to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Chicago to St. Louis from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from Chicago to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Chicago and St. Louis?
Frequently asked questions on the trip Chicago - St. Louis
How far is St. Louis from Chicago by coach?
The journey from Chicago to St. Louis by coach covers an approximate distance of 260 miles (419 km).
Is there a way to reach St. Louis from Chicago without flying?
You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to St. Louis as early as possible.
You can expect to pay from US$33 to US$108 for a bus ticket from Chicago to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$33, which is on 2025-09-10.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Chicago to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to St. Louis, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to St. Louis that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to St. Louis.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top travelled bus routes
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Popular Buses Connecting Chicago
Buses Leaving from Chicago
- Bus from Chicago to Columbia
- Coach Chicago - Seattle
- Bus Chicago - Toronto
- Chicago - Orlando
- Bus from Chicago to Mexico City
- Coach Chicago - Washington
- Bus Chicago - Madison
- Chicago - Green Bay
- Bus from Chicago to Indianapolis
- Coach Chicago - New York City
- Bus Chicago - Milwaukee
- Chicago - South Bend
- Bus from Chicago to Detroit
- Coach Chicago - Champaign
- Bus Chicago - Rockford
Buses Going to Chicago
- Bus from Boston to Chicago
- Coach Toronto - Chicago
- Bus Indianapolis - Chicago
- Atlanta - Chicago
- Bus from Bridgeport to Chicago
- Coach Auburn - Chicago
- Bus Madison - Chicago
- New York City - Chicago
- Bus from Columbus to Chicago
- Coach Milwaukee - Chicago
- Bus Green Bay - Chicago
- Washington - Chicago
- Bus from Rockford to Chicago
- Coach Kenosha - Chicago
- Bus Ann Arbor - Chicago
Popular Buses Connecting St. Louis
Buses Leaving from St. Louis
- Bus from St. Louis to New Orleans
- Coach St. Louis - Kansas City
- Bus St. Louis - Kansas City
- St. Louis - Buffalo
- Bus from St. Louis to Nashville
- Coach St. Louis - Austin
- Bus St. Louis - Newark
- St. Louis - Davenport
- Bus from St. Louis to Richmond
- Coach St. Louis - Lafayette
- Bus St. Louis - Columbia
- St. Louis - San Diego
- Bus from St. Louis to Lakeland
- Coach St. Louis - Ruston
- Bus St. Louis - Chicago
Buses Going to St. Louis
- Bus from Manchester to St. Louis
- Coach Manchester - St. Louis
- Bus New Orleans - St. Louis
- Indianapolis - St. Louis
- Bus from Atlanta to St. Louis
- Coach Burlington - St. Louis
- Bus Los Angeles - St. Louis
- Springfield - St. Louis
- Bus from Memphis to St. Louis
- Coach New York City - St. Louis
- Bus Des Moines - St. Louis
- Dallas - St. Louis
- Bus from Chicago to St. Louis
- Coach Spartanburg - St. Louis
- Bus Cincinnati - St. Louis
Popular routes in this country
- Bus from Niagara Falls to New York City
- Coach Atlanta - Savannah
- Bus Philadelphia - New York City
- Tallahassee - Panama City
- Bus from Baton Rouge to New Orleans
- Coach Las Vegas - Los Angeles
- Bus Chicago - Cleveland
- Washington - Baltimore
- Bus from New York City to Niagara Falls
- Coach Houston - Dallas
- Bus Atlanta - Nashville
- Baltimore - New York City
- Bus from Orlando to Fort Lauderdale
- Coach Dallas - Houston
- Bus New York City - Baltimore
Popular airport transfers
- Travel in United States
- Bus to Chicago
- Bus to St. Louis
- Chicago to St. Louis Buses