Bus Tickets from Jacksonville (NC) to Knoxville (TN)

Find affordable bus tickets from Jacksonville (NC) to Knoxville (TN) with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Bus Jacksonville to Knoxville: Trip Overview

Average Ticket PriceUS$61
Average Bus Trip Duration1d 2h
Number of daily buses1
Earliest bus departure4:00pm
Distance602 km

Jacksonville to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jacksonville to Knoxville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Jacksonville to Knoxville.

From cheap bus tickets to more luxurious buses travelling from Jacksonville to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Jacksonville (NC) - Knoxville (TN)

  1. How long does it take to get to Knoxville from Jacksonville by bus?

    The bus ride from Jacksonville to Knoxville takes 1d 2h, on average. For the shortest travel time, select the fastest bus available, which will take you to Knoxville in about 1d 2h.

  2. What is the distance between Jacksonville and Knoxville?

    Jacksonville and Knoxville are 606 km (376 miles) apart.

  3. What is the cheapest way to get from Jacksonville to Knoxville?

    The least expensive way to go from Jacksonville to Knoxville would be going by bus. Starting at US$61, this bus is the most cost-effective option for your journey.

  4. How much is the bus from Jacksonville to Knoxville?

    The bus from Jacksonville to Knoxville will cost you US$61, on average.

  5. Is it possible to travel by overnight bus from Jacksonville to Knoxville?

    Yes! If you're heading from Jacksonville to Knoxville, you'll find buses departing until 4:00pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-13
No data
06-14
No data
Today
No data
06-16
No data
06-17
No data
06-18
US$54
06-19
No data
06-20
No data
busbud logoThe cheapest trip from Jacksonville to Knoxville was searched and found on Jun 18, 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville to Knoxville, as early as possible.

You can expect to pay from US$54 to US$54 for a bus ticket from Jacksonville to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at US$54 which is on 2025-06-18.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jacksonville to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Jacksonville to Knoxville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Jacksonville to Knoxville that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Jacksonville to Knoxville.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Jacksonville by bus?

Bus from Jacksonville to Knoxville

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Jacksonville

Buses Leaving from Jacksonville

Buses Going to Jacksonville

Popular Buses Connecting Knoxville

Buses Leaving from Knoxville

Buses Going to Knoxville