Bus Jacksonville to Knoxville: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Jacksonville to Knoxville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jacksonville to Knoxville.
We make it our job to connect you with the most dependable bus companies that cover bus service from Jacksonville to Knoxville.
From cheap bus tickets to more luxurious buses traveling from Jacksonville to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Jacksonville (NC) - Knoxville (TN)
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville to Knoxville was searched and found on Jun 18, 2025 with a price of $54To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville to Knoxville, as early as possible.
You can expect to pay from $54 to $54 for a bus ticket from Jacksonville to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at $54 which is on 2025-06-18.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jacksonville to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Jacksonville to Knoxville.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Jacksonville to Knoxville that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Jacksonville to Knoxville.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top traveled bus routes
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The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Jacksonville
Buses Leaving from Jacksonville
Buses Going to Jacksonville
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Orlando
- Bus Knoxville - Chicago
- Knoxville - New York
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to Washington
- Bus Knoxville - Miami
- Knoxville - Jackson
- Bus from Knoxville to Cincinnati
- Bus Knoxville - Dallas
- Knoxville - Greenville
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Richmond - Knoxville
- Bus from Atlanta to Knoxville
- Bus New York - Knoxville
- Greenville - Knoxville
- Bus from Cookeville to Knoxville
- Bus Louisville - Knoxville
- Dallas - Knoxville
- Bus from Lexington to Knoxville
- Bus Baltimore - Knoxville
- Cincinnati - Knoxville