Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | BILOXI | Knoxville Bus Station | CheapestFastest |
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Bus Biloxi to Knoxville, TN: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Biloxi to Knoxville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Biloxi to Knoxville.
We make it our job to connect you with the most dependable bus companies that cover bus service from Biloxi to Knoxville.
Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Biloxi, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Biloxi and Knoxville?
Frequently asked questions for your trip Biloxi - Knoxville, TN
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Biloxi to Knoxville, TN was searched and found on Aug 22, 2025 with a price of $111To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Biloxi to Knoxville, TN, as early as possible.
You can expect to pay from $111 to $122 for a bus ticket from Biloxi to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $122 which is on 2025-08-23.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Biloxi to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Biloxi to Knoxville.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Biloxi to Knoxville.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Biloxi to Knoxville.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Biloxi
Buses Leaving from Biloxi
- Bus from Biloxi to New Orleans
- Bus Biloxi - Las Vegas
- Biloxi - Washington
- Bus from Biloxi to Pensacola
- Bus Biloxi - Houston
- Biloxi - Atlanta
- Bus from Biloxi to Tupelo
- Bus Biloxi - Orlando
- Biloxi - Dallas
- Bus from Biloxi to Mobile
- Bus Biloxi - Shreveport
- Biloxi - Tyler
- Bus from Biloxi to Memphis
- Bus Biloxi - Montgomery
- Biloxi - Tallahassee
Buses Going to Biloxi
- Bus from New Orleans to Biloxi
- Bus Chicago - Biloxi
- Lexington - Biloxi
- Bus from Madison to Biloxi
- Bus Mobile - Biloxi
- Pensacola - Biloxi
- Bus from Panama City to Biloxi
- Bus Memphis - Biloxi
- Houston - Biloxi
- Bus from Atlanta to Biloxi
- Bus Tampa - Biloxi
- Baton Rouge - Biloxi
- Bus from Birmingham to Biloxi
- Bus Orlando - Biloxi
- Lafayette - Biloxi
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Orlando
- Bus from Knoxville to Lexington
- Bus Knoxville - Chicago
- Knoxville - Greenville
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - New York City
- Bus from Knoxville to Memphis
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Miami
- Bus Knoxville - Jackson
- Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Asheville - Knoxville
- New York City - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Cookeville - Knoxville
- Bus from Lexington to Knoxville
- Bus Dallas - Knoxville
- Dayton - Knoxville