Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
A Texas-based company, Tornado Bus operates throughout the United States, with routes connecting major cities, including Houston, San Antonio and El Paso. Each day,1 buses leave from their terminals to destinations across the continent. Their buses are equipped with free Wi-Fi, air conditioning, bathrooms, power outlets and a comfortable amount of legroom. With prices as low as $347 for a short ride, Tornado offers options for budget travelers, without compromising comfort. and those looking for a little luxury. The company requires printed tickets for boarding and their tickets are non-refundable, but you can exchange them up to two hours before travel time for a fee. With a friendly staff and multiple routes, traveling with Tornado is a convenient way to get around.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Chicago to Biloxi by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Biloxi?
The cheapest bus tickets from Chicago to Biloxi start from $148. The average price for this route is around $261. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Biloxi?
The average bus trip duration from Chicago to Biloxi is 1d 5h, covering a distance of 788 miles (1270 km). The quickest bus can get you there in 1d 1h and is operated by FlixBus.
Which bus companies service the Chicago to Biloxi route?
Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, Tornado Bus, FlixBus.
What is the earliest and latest departure time for the bus from Chicago to Biloxi?
The earliest bus departs from Chicago to Biloxi at 10:00am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Chicago to Biloxi?
A bus trip from Chicago to Biloxi generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Chicago to Biloxi?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Chicago to Biloxi?
Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 3.9.
Which bus company has the most timely service from Chicago to Biloxi?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Biloxi?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/24
$181
12/25
$232
Today
$270
12/27
$293
12/28
$176
12/29
$158
12/30
$161
12/31
No data
The cheapest trip from Chicago to Biloxi was searched and found on Dec 29, 2025 with a price of $158
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Biloxi, as early as possible.
You can expect to pay from $158 to $344 for a bus ticket from Chicago to Biloxi based on the last 2 days. You can expect to find the cheapest price for the trip at $158 which is on 2025-12-29.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Chicago to Biloxi was searched and found on Dec 29, 2025 with a price of $158
