Find coaches from Tampa to Greenville, SC

Next departures

Next departures from Tampa to Greenville on 31 August
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Tampa Bus Station
1116 Woodruff RdCheapest
FlixBus + Greyhound Lines, Inc.
University of South Florida
1116 Woodruff RdFastest
Amtrak
Union Station
Greenville StationNo tags
FlixBus
Tampa Bus Station
1116 Woodruff RdNo tags
FlixBus + Greyhound Lines, Inc.
Tampa Bus Station
1116 Woodruff RdNo tags

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Compare 2 ways to travel from Tampa to Greenville

Average priceUS$81 - US$169Average duration14h 40m
19kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average priceUS$193 - US$221Average duration1d 12h
70kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Tampa to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 14 hours 40 minutes and with fares starting at just US$81, it presents an excellent value for a comfortable ride.

5bus per day
14h 40mAverage duration
US$81Cheapest ticket
19kgCO₂ emissions

Bus Tampa to Greenville, SC: Trip Overview

Average ticket priceUS$106
Average bus trip duration14h 40m
Number of daily buses5
Earliest bus departure06:20
Distance475 miles
Latest bus departure22:35

Tampa to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Tampa to Greenville.

Bus service from Tampa to Greenville will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Tampa, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Tampa - Greenville, SC

  1. How far is Greenville from Tampa by coach?

    The distance between Tampa and Greenville by coach is approximately 477 miles (769 km).

  2. Is there a way to reach Greenville from Tampa without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/08
US$565
29/08
US$108
Today
US$78
31/08
US$86
01/09
US$95
02/09
No data
03/09
No data
04/09
No data
busbud logoThe cheapest trip from Tampa to Greenville, SC was searched and found on 30 Aug 2025 with a price of US$78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Greenville, SC as early as possible.

You can expect to pay from US$78 to US$2,234 for a bus ticket from Tampa to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$86, which is on 2025-08-31.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Tampa to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Tampa to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to Greenville.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Tampa to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Tampa by bus?

Bus from Greenville, SC to Tampa

You can also go to Greenville, SC by train

Train from Tampa to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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