Bus Tickets from Tampa to Greenville, SC

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TodayAug 30
from US$85
TomorrowAug 31
from US$90
MonSep 1
TueSep 2
WedSep 3
ThuSep 4
FriSep 5
SatSep 6

Next departures to Greenville

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 31 at
    Departure city: Tampa
    Departure location: Tampa Bus Station
    Arrival time: September 1 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 31 at
    Departure city: Tampa
    Departure location: University of South Florida
    Arrival time: September 1 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Tampa
    Departure location: Union Station
    Arrival time: September 2 at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Tampa
    Departure location: Tampa Bus Station
    Arrival time: August 31 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Tampa
    Departure location: Tampa Bus Station
    Arrival time: September 1 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Tampa to Greenville

Average PriceUS$81 - US$169Average Duration14h 40m
19kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$193 - US$221Average Duration1d 12h
70kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Tampa to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 14 hours 40 minutes, and with fares starting at just US$81, it presents an excellent value for a comfortable ride.

5bus per day
14h 40mAverage Duration
US$81Cheapest ticket
19kgCO₂ emissions

Bus Tampa to Greenville, SC: Trip Overview

Average Ticket PriceUS$106
Average Bus Trip Duration14h 40m
Number of daily buses5
Earliest bus departure6:20am
Distance765 km
Latest bus departure10:35pm

Tampa to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Tampa to Greenville.

Bus service from Tampa to Greenville will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Tampa, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Tampa - Greenville, SC

  1. What is the travel distance from Tampa to Greenville?

    The distance between Tampa and Greenville is around 769 km (477 miles).

  2. What are the departure and arrival locations for buses traveling from Tampa to Greenville?

    Buses traveling this route start their trip at Tampa 13th Avenue Bus Stop (McDonald's), in Tampa, and end it at Guadalajara Supermarket Bus Stop, in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-28
US$565
08-29
US$108
Today
US$78
08-31
US$86
09-01
US$95
09-02
No data
09-03
No data
09-04
No data
busbud logoThe cheapest trip from Tampa to Greenville, SC was searched and found on Aug 30, 2025 with a price of US$78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Greenville, SC, as early as possible.

You can expect to pay from US$78 to US$2,234 for a bus ticket from Tampa to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$86 which is on 2025-08-31.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Tampa to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Tampa to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to Greenville.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Tampa to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Tampa by bus?

Bus from Greenville, SC to Tampa

You can also go to Greenville, SC by train

Train from Tampa to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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