Find coaches from San Diego, CA, US to Louisville

Find affordable coach tickets from San Diego, CA, US to Louisville with flexible options. Book your journey now

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Previously seen journeys

One passenger / one way

  • Departure time: 26 November at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: 28 November at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 26 November at
    Departure city: San Diego
    Departure location: 5716 Hardy Ave
    Arrival time: 29 November at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 November at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: 29 November at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 November at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: 29 November at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 November at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: 29 November at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Compare 2 ways to travel from San Diego to Louisville

Bus
Average priceUS$139 - US$544Average duration2d 4h
72kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$263 - US$371Average duration2d 12h
263kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Diego to Louisville

Among the sustainable travel choices, the bus stands out as a good way to reach Louisville. The journey takes about 2 days, 4 hours 15 minutes and with fares starting at just US$139, it presents an excellent value for a comfortable ride.

10bus per day
2d 4hAverage duration
US$139Cheapest ticket
72kgCO₂ emissions

Bus San Diego, CA, US to Louisville: Trip Overview

Average ticket priceUS$183
Average bus trip duration2d 4h
Number of daily buses10
Earliest bus departure07:15
Distance1795 miles
Latest bus departure19:35

San Diego to Louisville Bus

Busbud helps you find a bus from San Diego to Louisville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Louisville.

From cheap bus tickets to more luxurious buses travelling from San Diego to Louisville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Diego, CA, US - Louisville

  1. What's the distance between San Diego and Louisville by coach?

    The journey from San Diego to Louisville by coach covers an approximate distance of 1797 miles (2898 km).

  2. How can I travel from San Diego to Louisville avoiding air travel?

    To travel from San Diego to Louisville without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
02/09
US$165
03/09
No data
Today
US$203
05/09
No data
06/09
US$163
07/09
No data
08/09
No data
09/09
US$139
busbud logoThe cheapest trip from San Diego, CA, US to Louisville was searched and found on 9 Sept 2025 with a price of US$139

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Louisville as early as possible.

You can expect to pay from US$139 to US$206 for a bus ticket from San Diego, CA, US to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at US$139, which is on 2025-09-09.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Louisville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Diego to Louisville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Louisville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Diego to Louisville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from San Diego, CA, US to Louisville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego, CA, US by bus?

Bus from Louisville to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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