Bus from Philadelphia, PA to Florence, SC, US: Tickets & Timetables

Next bus departures

Next departures from Philadelphia to Florence on 26 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Philadelphia, 199 Spring Garden St
Florence, SCCheapestFastest
Greyhound Lines, Inc.Bus
199 Spring Garden St.
Bus stationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Florence, SCNo tags
FlixBusBus
Cherry Hill Mall
Florence, SCNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
Bus stationNo tags

Last refresh of the prices: Yesterday at 11:01 EST.

Compare 2 ways to travel from Philadelphia to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 10 hours 55 minutes and with fares starting at just £69, it presents an excellent value for a comfortable ride.

1train per day
10h 55mAverage duration
470 milesDistance
69kgCO₂ emissions
Average price£67 - £250Average duration15h 45m
19kg CO₂e
Average price£69 - £967Average duration10h 55m
69kg CO₂e

Frequently asked questions about travelling by bus from Philadelphia, PA to Florence, SC, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Philadelphia to Florence?

    The cheapest coach tickets from Philadelphia to Florence start from £67. The average price for this route is around £103. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Philadelphia to Florence?

    The average bus journey time from Philadelphia to Florence is 15h 45m, covering a distance of 475 miles. The fastest bus can take you there in 11h 15m and is operated by FlixBus.

  3. Which bus companies service the Philadelphia to Florence route?

    Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Philadelphia to Florence?

    The earliest bus departs from Philadelphia to Florence at 10:40. And the latest bus departs at 22:00.

  5. What are the CO₂ emissions for the bus trip from Philadelphia to Florence?

    A bus journey from Philadelphia to Florence produces an estimated 19 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Philadelphia to Florence?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11638 reviews.

  7. Which company has the best Wi-Fi from Philadelphia to Florence?

    Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Philadelphia to Florence?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Philadelphia to Florence?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/12
£129
25/12
£97
Today
£107
27/12
£98
28/12
£98
29/12
£73
30/12
£63
31/12
No data
busbud logoThe cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on 30 Dec 2025 with a price of £63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US as early as possible.

You can expect to pay from £63 to £177 for a bus ticket from Philadelphia, PA to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £63, which is on 2025-12-30.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Philadelphia, PA to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

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