Find coaches from Philadelphia, PA to Florence, SC, US

Today31 Jul
from US$109
Tomorrow1 Aug
from US$109
Sat2 Aug
from US$107
Sun3 Aug
from US$99
Mon4 Aug
from US$86
Tue5 Aug
from US$88
Wed6 Aug
Thu7 Aug
from US$97

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 1 August at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 2 August at
    Destination city: Florence
    Destination location: Bus station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 1 August at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 2 August at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 2 August at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 2 August at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 2 August at
    Destination city: Florence
    Destination location: Bus station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Philadelphia to Florence

Bus
Average priceUS$67 - US$263Average duration16h 45m
19kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$91 - US$356Average duration10h 55m
69kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Philadelphia to Florence

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 10 hours 55 minutes and with fares starting at just US$91, it presents an excellent value for a comfortable ride.

1train per day
10h 55mAverage duration
US$91Cheapest ticket
69kgCO₂ emissions

Bus Philadelphia, PA to Florence, SC, US: Trip Overview

Average ticket priceUS$117
Average bus trip duration16h 45m
Number of daily buses9
Earliest bus departure07:05
Distance472 miles
Latest bus departure23:15

Philadelphia to Florence Bus

Busbud helps you find a bus from Philadelphia to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Florence.

Discover how much the bus trip from Philadelphia to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Philadelphia, PA - Florence, SC, US

  1. How far is Florence from Philadelphia by coach?

    The distance between Philadelphia and Florence by coach is approximately 467 miles (753 km).

  2. Is there a way to reach Florence from Philadelphia without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/07
US$151
30/07
US$134
Today
US$161
01/08
US$225
02/08
US$136
03/08
US$117
04/08
US$105
05/08
US$118
busbud logoThe cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on 4 Aug 2025 with a price of US$105

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US as early as possible.

You can expect to pay from US$105 to US$228 for a bus ticket from Philadelphia, PA to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$105, which is on 2025-08-04.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Philadelphia and Florence!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Florence.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Philadelphia to Florence will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Philadelphia to Florence while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Philadelphia, PA to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia, PA by bus?

Bus from Philadelphia, PA to Florence, SC, US

You can also go to Florence, SC, US by train

Train from Philadelphia, PA to Florence, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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