Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Schuylkill & Walnut | Bus station | Cheapest | |||||
 | Philadelphia, 199 Spring Garden St | Florence, SC | Fastest | |||||
Greyhound Lines, Inc. + FlixBus | 199 Spring Garden St. | Bus station | No tags | |||||
| Cherry Hill Mall | Florence, SC | No tags | |||||
Greyhound Lines, Inc. + FlixBus | 199 Spring Garden St. | Florence, SC | No tags |
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Compare 2 ways to travel from Philadelphia to Florence
Busbud recommends taking the train from Philadelphia to FlorenceAmong the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 10 hours 22 minutes and with fares starting at just US$97, it presents an excellent value for a comfortable ride.
Bus Philadelphia, PA to Florence, SC, US: Trip Overview
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Philadelphia to Florence Bus
Busbud helps you find a bus from Philadelphia to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Florence.
Discover how much the bus trip from Philadelphia to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Philadelphia and Florence?
Frequently asked questions on the trip Philadelphia, PA - Florence, SC, US
How far is Florence from Philadelphia by coach?
The distance between Philadelphia and Florence by coach is approximately 467 miles (753 km).
Is there a way to reach Florence from Philadelphia without flying?
You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on 20 Sept 2025 with a price of US$75To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US as early as possible.
You can expect to pay from US$75 to US$106 for a bus ticket from Philadelphia, PA to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$75, which is on 2025-09-20.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Philadelphia and Florence!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Florence.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Philadelphia to Florence will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Philadelphia to Florence while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
What's the cheapest way to go from Philadelphia, PA to Florence, SC, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Philadelphia
Buses Leaving from Philadelphia
- Bus from Philadelphia to Richmond
- Coach Philadelphia - Washington
- Bus Philadelphia - Washington
- Philadelphia - Washington
- Bus from Philadelphia to Hamilton
- Coach Philadelphia - Queens Village
- Bus Philadelphia - Baltimore
- Philadelphia - Daytona Beach
- Bus from Philadelphia to Atlantic City
- Coach Philadelphia - Miami
- Bus Philadelphia - Newark
- Philadelphia - Scranton
- Bus from Philadelphia to Chicago
- Coach Philadelphia - Boston
- Bus Philadelphia - Springfield
Buses Going to Philadelphia
- Bus from Marathon to Philadelphia
- Coach North East - Philadelphia
- Bus Pittsburgh - Philadelphia
- Boston - Philadelphia
- Bus from Washington to Philadelphia
- Coach Washington - Philadelphia
- Bus Newark - Philadelphia
- Savannah - Philadelphia
- Bus from Allentown to Philadelphia
- Coach Reading - Philadelphia
- Bus Scranton - Philadelphia
- Baltimore - Philadelphia
- Bus from Easton to Philadelphia
- Coach Albany - Philadelphia
- Bus Richmond - Philadelphia
Popular Buses Connecting Florence
Buses Leaving from Florence
- Bus from Florence to Kansas City
- Coach Florence - Kansas City
- Bus Florence - Oklahoma City
- Florence - Birmingham
- Bus from Florence to Houston
- Coach Florence - Montgomery
- Bus Florence - Opelika
- Florence - Chicago
- Bus from Florence to Cincinnati
- Coach Florence - Colorado Springs
- Bus Florence - Sarasota
- Florence - Orlando
- Bus from Florence to Columbus
- Coach Florence - Gary
- Bus Florence - Allentown
Buses Going to Florence
- Bus from Syracuse to Florence
- Coach Manchester - Florence
- Bus Columbus - Florence
- Columbus - Florence
- Bus from Los Angeles to Florence
- Coach Toronto - Florence
- Bus Fort Lauderdale - Florence
- Greensboro - Florence
- Bus from Phoenix to Florence
- Coach Washington - Florence
- Bus Opelika - Florence
- Miami - Florence
- Bus from New York City to Florence
- Coach Panama City - Florence
- Bus Charleston - Florence
Popular routes in this country
- Bus from Niagara Falls to New York City
- Coach Atlanta - Savannah
- Bus Philadelphia - New York City
- Tallahassee - Panama City
- Bus from Baton Rouge to New Orleans
- Coach Las Vegas - Los Angeles
- Bus Chicago - Cleveland
- Washington - Baltimore
- Bus from New York City to Niagara Falls
- Coach Houston - Dallas
- Bus Atlanta - Nashville
- Baltimore - New York City
- Bus from Dallas to Houston
- Coach Orlando - Fort Lauderdale
- Bus New York City - Baltimore