How much is the bus ticket from Philadelphia to Florence?

The cheapest bus tickets from Philadelphia to Florence start from $81. The average price for this route is around $129. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Philadelphia to Florence?

The average bus trip duration from Philadelphia to Florence is 15h 45m, covering a distance of 473 miles (762 km). The quickest bus can get you there in 11h 15m and is operated by FlixBus .

Which bus companies service the Philadelphia to Florence route?

Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Philadelphia to Florence?

The earliest bus departs from Philadelphia to Florence at 10:40am. And the latest bus departs at 10:00pm.

What are the CO₂ emissions for the bus trip from Philadelphia to Florence?

A bus trip from Philadelphia to Florence generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Philadelphia to Florence?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11504 reviews.

Which bus company has the best Wi-Fi from Philadelphia to Florence?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Philadelphia to Florence?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Philadelphia to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Philadelphia to Florence from $83 | Refundable Tickets

Next bus departures

Next departures for Philadelphia to Florence on December 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	Philadelphia, 199 Spring Garden St	13h 45m	11:45am	Bus station	CheapestFastest
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	No tags
	Bus	8:00pm	Schuylkill & Walnut	15h 45m	11:45am	Bus station	No tags

Next departures for Philadelphia to Florence on December 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	6:30pm	Philadelphia, 199 Spring Garden St	17h 15m	11:45am	Bus station	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	11h 15m	5:45am	Florence, SC	Fastest
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:50pm	199 Spring Garden St.	11h 55m	5:45am	Florence, SC	No tags
	Bus	10:40am	Philadelphia (Logan Square)	19h 5m	5:45am	Florence, SC	No tags

Next departures for Philadelphia to Florence on December 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	6:45pm	Philadelphia, 199 Spring Garden St	17h	11:45am	Bus station	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	11h 15m	5:45am	Florence, SC	Fastest
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:50pm	199 Spring Garden St.	11h 55m	5:45am	Florence, SC	No tags
	Bus	11:00am	Cherry Hill Mall	18h 45m	5:45am	Florence, SC	No tags

Next departures for Philadelphia to Florence on December 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	Philadelphia, 199 Spring Garden St	13h 45m	11:45am	Bus station	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	11h 15m	5:45am	Florence, SC	Fastest
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:50pm	199 Spring Garden St.	11h 55m	5:45am	Florence, SC	No tags
	Bus	11:00am	Cherry Hill Mall	18h 45m	5:45am	Florence, SC	No tags

Last refresh of the prices: Yesterday at 5:58 PM EST.

Compare 2 ways to go from Philadelphia to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 10 hours 22 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.

2train per day

10h 22mAverage Duration

470 milesDistance

69kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$81 - $329	Average Duration15h 45m	CO₂ emissions 19kg CO₂e
Train	Average Price$91 - $1,274	Average Duration10h 22m	CO₂ emissions 69kg CO₂e

Where are the popular stops in Philadelphia and Florence?

Stops in Philadelphia

A
Philadelphia Airport
Visit page
B
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
Visit page
C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA
D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA
E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA
F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/511,629 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,434 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Philadelphia, PA to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Philadelphia to Florence?
The cheapest bus tickets from Philadelphia to Florence start from $81. The average price for this route is around $129. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Philadelphia to Florence?
The average bus trip duration from Philadelphia to Florence is 15h 45m, covering a distance of 473 miles (762 km). The quickest bus can get you there in 11h 15m and is operated by FlixBus.
Which bus companies service the Philadelphia to Florence route?
Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Philadelphia to Florence?
The earliest bus departs from Philadelphia to Florence at 10:40am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Philadelphia to Florence?
A bus trip from Philadelphia to Florence generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Philadelphia to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which bus company has the best Wi-Fi from Philadelphia to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Philadelphia to Florence?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/14

$120

12/15

$87

Today

$128

12/17

$117

12/18

$110

12/19

$126

12/20

$120

12/21

$121

The cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on Dec 15, 2025 with a price of $87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US, as early as possible.

You can expect to pay from $87 to $173 for a bus ticket from Philadelphia, PA to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2025-12-18.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.