Bus Tickets from Florence, SC, US to Boston, MA, US

Next departures

Next departures for Florence to Boston on September 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus station
151 Steel Pl, CambridgeCheapest
FlixBus + Greyhound Lines, Inc.
Florence, SC
Boston (South Station)Fastest
FlixBus + Greyhound Lines, Inc.
Bus station
Boston (South Station)No tags
FlixBus + Greyhound Lines, Inc.
Florence, SC
Boston (South Station)No tags
FlixBus + Greyhound Lines, Inc.
Florence, SC
BrooklineNo tags

Accepted payments

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Compare 2 ways to go from Florence to Boston.

Bus
Average Price$78 - $398Average Duration1d 3h
30kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$164 - $572Average Duration22h 48m
106kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Florence to Boston

Among the sustainable travel choices, the bus stands out as the good way to reach Boston. The journey takes about 1 day, 3 hours 5 minutes and with fares starting at just $78, it presents an excellent value for a comfortable ride.

5bus per day
1d 3hAverage Duration
$78Cheapest ticket
30kgCO₂ emissions

Bus Florence, SC, US to Boston, MA, US: Trip Overview

Average ticket price$142
Average bus trip duration1d 3h
Number of daily buses5
Earliest bus departure12:05am
Distance733 miles (1182 km)
Latest bus departure4:15pm

Florence to Boston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Boston.

We make sure you can find a bus service from Florence to Boston from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Florence to Boston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Florence, SC, US - Boston, MA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/28
No data
08/29
No data
Today
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08/31
No data
09/01
No data
09/02
$113
09/03
$124
09/04
No data
busbud logoThe cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Sep 2, 2025 with a price of $113

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from $113 to $124 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $113 which is on 2025-09-02.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Boston but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Boston, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Boston that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Boston while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Florence, SC, US to Boston, MA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Boston, MA, US to Florence, SC, US

You can also go to Boston, MA, US by train

Train from Florence, SC, US to Boston, MA, US

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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