How much is the bus ticket from Philadelphia to Florence?

The cheapest bus tickets from Philadelphia to Florence start from $123. The average price for this route is around $189. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Philadelphia to Florence?

The average bus travel time from Philadelphia to Florence is 15h 45m, covering a distance of 766 km. The quickest bus can get you there in 11h 15m and is operated by FlixBus .

Which bus companies service the Philadelphia to Florence route?

Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus , Greyhound .

What are the earliest and latest departure times for the bus from Philadelphia to Florence?

The earliest bus departs from Philadelphia to Florence at 10:40am. And the latest bus departs at 10:00pm.

What are the CO₂ emissions for the bus trip from Philadelphia to Florence?

A bus trip from Philadelphia to Florence generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Philadelphia to Florence?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11638 reviews.

Which bus company has the best Wi-Fi from Philadelphia to Florence?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Philadelphia to Florence?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Philadelphia to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Philadelphia to Florence from $86 | Refundable Tickets

Next bus departures

Next departures for Philadelphia to Florence on December 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	Philadelphia (Logan Square)	21h 45m	11:45am	Bus station	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	11h 15m	5:45am	Florence, SC	Fastest
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:50pm	199 Spring Garden St.	11h 55m	5:45am	Florence, SC	No tags
	Bus	11:00am	Cherry Hill Mall	18h 45m	5:45am	Florence, SC	No tags

Last refresh of the prices: Today at 1:02 PM EST.

Compare 2 ways to go from Philadelphia to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 10 hours 55 minutes, and with fares starting at just $127, it presents an excellent value for a comfortable ride.

1train per day

10h 55mAverage Duration

758 kmDistance

69kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$123 - $461	Average Duration15h 45m	CO₂ emissions 19kg CO₂e
Train	Average Price$127 - $1,785	Average Duration10h 55m	CO₂ emissions 69kg CO₂e

Where are the popular stops in Philadelphia and Florence?

Stops in Philadelphia

A
Philadelphia Airport
Visit page
B
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
Visit page
C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA
D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA
E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA
F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/511,726 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Greyhound

3.5/587,449 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Philadelphia, PA to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Philadelphia to Florence?
The cheapest bus tickets from Philadelphia to Florence start from $123. The average price for this route is around $189. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Philadelphia to Florence?
The average bus travel time from Philadelphia to Florence is 15h 45m, covering a distance of 766 km. The quickest bus can get you there in 11h 15m and is operated by FlixBus.
Which bus companies service the Philadelphia to Florence route?
Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus, Greyhound.
What are the earliest and latest departure times for the bus from Philadelphia to Florence?
The earliest bus departs from Philadelphia to Florence at 10:40am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Philadelphia to Florence?
A bus trip from Philadelphia to Florence generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Philadelphia to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11638 reviews.
Which bus company has the best Wi-Fi from Philadelphia to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Philadelphia to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-22

$302

12-23

$341

Today

$239

12-25

$174

12-26

$242

12-27

$181

12-28

$180

12-29

$135

The cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on Dec 29, 2025 with a price of $135

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US, as early as possible.

You can expect to pay from $135 to $436 for a bus ticket from Philadelphia, PA to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $135 which is on 2025-12-29.

Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.