Find coaches from New Orleans to Greenville (SC)

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Today5 Jun
Tomorrow6 Jun
Sat7 Jun
Sun8 Jun
Mon9 Jun
Tue10 Jun
Wed11 Jun
from US$138
Thu12 Jun

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 11 June at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: 12 June at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 11 June at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: 12 June at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 11 June at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: 12 June at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from New Orleans to Greenville

Bus
Average priceUS$91 - US$201Average duration17h 30m
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$134 - US$163Average duration16h 3m
82kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from New Orleans to Greenville

Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 16 hours 3 minutes and with fares starting at just US$134, it presents an excellent value for a comfortable ride.

1train per day
16h 3mAverage duration
US$134Cheapest ticket
82kgCO₂ emissions

Bus New Orleans to Greenville: Trip Overview

Average ticket priceUS$156
Average bus trip duration17h 30m
Number of daily buses3
Earliest bus departure05:10
Distance564 miles
Latest bus departure23:35

New Orleans to Greenville Bus

With Busbud, comparing and booking tickets for a bus from New Orleans to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from New Orleans to Greenville from the most reliable bus companies operating this trip.

Discover how much the bus trip from New Orleans to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip New Orleans - Greenville (SC)

  1. How much does it cost to go to Greenville by bus?

    Coach ticket prices from New Orleans to Greenville can start as low as US$91, though the average price for this trip is US$156. These prices can change depending on factors like the date, the class and the coach company you choose. Keep in mind that booking tickets on the day of travel might result in higher prices.

  2. How long is a coach from New Orleans to Greenville?

    The coach journey between New Orleans and Greenville lasts about 17h 30m. The quickest coach journey typically takes 12h 30m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from New Orleans to Greenville?

    The first coach from New Orleans to Greenville leaves at 05:10. Keep in mind that departure times might change on weekends and holidays.

  4. What's the distance between New Orleans and Greenville by coach?

    The journey from New Orleans to Greenville by coach covers an approximate distance of 561 miles (905 km).

  5. What is the best way to go from New Orleans to Greenville without flying?

    To travel from New Orleans to Greenville without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

  6. Can I catch a night bus from New Orleans to Greenville?

    Yes, you can find buses leaving until 23:35 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/06
No data
04/06
US$162
Today
No data
06/06
No data
07/06
US$148
08/06
US$92
09/06
No data
10/06
No data
busbud logoThe cheapest trip from New Orleans to Greenville was searched and found on 8 Jun 2025 with a price of US$92

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Greenville as early as possible.

You can expect to pay from US$92 to US$168 for a bus ticket from New Orleans to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$92, which is on 2025-06-08.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from New Orleans to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New Orleans to Greenville, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from New Orleans to Greenville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from New Orleans to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from New Orleans to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to New Orleans by bus?

Bus from New Orleans to Greenville

You can also go to Greenville by train

Train from New Orleans to Greenville

Why choose Busbud?

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