Find coaches from Greenville, SC to New Orleans

Find affordable coach tickets from Greenville, SC to New Orleans with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Today29 Aug
Tomorrow30 Aug
from US$88
Sun31 Aug
from US$111
Mon1 Sept
from US$92
Tue2 Sept
from US$89
Wed3 Sept
from US$77
Thu4 Sept
from US$74
Fri5 Sept

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 30 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 31 August at
    Destination city: New Orleans
    Destination location: New Orleans Intl Airport, 900 Airline Dr
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 30 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 31 August at
    Destination city: New Orleans
    Destination location: New Orleans Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 30 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 31 August at
    Destination city: New Orleans
    Destination location: New Orleans Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 30 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 31 August at
    Destination city: New Orleans
    Destination location: New Orleans Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 30 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 31 August at
    Destination city: New Orleans
    Destination location: New Orleans Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Greenville to New Orleans

Average priceUS$73 - US$314Average duration19h 55m
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average priceUS$95 - US$517Average duration16h 41m
82kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Greenville to New Orleans

Among the sustainable travel choices, the train stands out as a good way to reach New Orleans. The journey takes about 16 hours 41 minutes and with fares starting at just US$95, it presents an excellent value for a comfortable ride.

1train per day
16h 41mAverage duration
US$95Cheapest ticket
82kgCO₂ emissions

Bus Greenville, SC to New Orleans: Trip Overview

Average ticket priceUS$92
Average bus trip duration19h 55m
Number of daily buses4
Earliest bus departure08:40
Distance571 miles
Latest bus departure22:00

Greenville to New Orleans Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to New Orleans.

Bus service from Greenville to New Orleans will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to New Orleans from Greenville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Greenville, SC - New Orleans

  1. How far is New Orleans from Greenville by coach?

    The journey from Greenville to New Orleans by coach covers an approximate distance of 561 miles (905 km).

  2. What is the best way to go from Greenville to New Orleans without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
27/08
US$67
28/08
US$94
Today
US$98
30/08
US$81
31/08
US$106
01/09
US$91
02/09
US$82
03/09
US$70
busbud logoThe cheapest trip from Greenville, SC to New Orleans was searched and found on 27 Aug 2025 with a price of US$67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to New Orleans as early as possible.

You can expect to pay from US$67 to US$108 for a bus ticket from Greenville, SC to New Orleans based on the last 2 days. You can expect to find the cheapest price for the trip at US$70, which is on 2025-09-03.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to New Orleans but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Greenville to New Orleans, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Greenville to New Orleans.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to New Orleans while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Greenville, SC to New Orleans?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from New Orleans to Greenville, SC

You can also go to New Orleans by train

Train from Greenville, SC to New Orleans

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville

Popular Buses Connecting New Orleans

Buses Leaving from New Orleans

Buses Going to New Orleans