Find coaches from Mesa to San Francisco, US

Next departures

Next departures from Mesa to San Francisco on 6 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Mesa Bus Stop
409 Townsend St, SFCheapest
Greyhound Lines, Inc.
Mesa Bus Stop
San Francisco Bus StationFastest
Greyhound Lines, Inc. + FlixBus
Mesa Bus Stop
409 Townsend St, SFNo tags
Greyhound Lines, Inc.
Mesa Bus Stop
San Francisco Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Mesa Bus Stop
San Francisco Bus StationNo tags

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Bus Mesa to San Francisco, US: Trip Overview

Average ticket priceUS$95
Average bus trip duration18h 35m
Number of daily buses4
Earliest bus departure13:45
Distance665 miles
Latest bus departure20:10

Mesa to San Francisco Bus

Busbud helps you find a bus from Mesa to San Francisco. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Mesa to San Francisco will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Mesa to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Mesa - San Francisco, US

  1. What's the distance between Mesa and San Francisco by coach?

    The distance between Mesa and San Francisco by coach is approximately 667 miles (1075 km).

  2. How can I travel from Mesa to San Francisco avoiding air travel?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/08
No data
31/08
No data
Today
No data
02/09
No data
03/09
No data
04/09
US$76
05/09
No data
06/09
US$87
busbud logoThe cheapest trip from Mesa to San Francisco, US was searched and found on 4 Sept 2025 with a price of US$76

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to San Francisco, US as early as possible.

You can expect to pay from US$76 to US$87 for a bus ticket from Mesa to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$76, which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mesa and San Francisco!

Much more than a mere vehicle taking you from Mesa to San Francisco, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mesa to San Francisco that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Mesa to San Francisco, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Mesa by bus?

Bus from San Francisco, US to Mesa

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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