Find coaches from Manchester, NH, US to Knoxville, TN

With Busbud, comparing and booking tickets for a bus from Manchester to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Manchester to Knoxville will be provided by the most trusted bus companies.

Discover how much the bus trip from Manchester to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Manchester to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Manchester to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Manchester to Knoxville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Manchester to Knoxville.