Find coaches from Knoxville, TN to Durham, NC, US

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Today20 Jun
from US$81
Tomorrow21 Jun
from US$103
Sun22 Jun
from US$120
Mon23 Jun
from US$93
Tue24 Jun
from US$93
Wed25 Jun
Thu26 Jun
from US$104
Fri27 Jun
from US$107

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 21 June at
    Departure city: Knoxville
    Departure location: Knoxville Bus Station
    Arrival time: 22 June at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Knoxville to Durham: Trip Overview

Average ticket priceUS$102
Average bus trip duration13h 35m
Number of daily buses1
Earliest bus departure19:20
Distance278 miles
Latest bus departure19:25

Knoxville to Durham Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Durham.

We make sure you can find a bus service from Knoxville to Durham from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Knoxville to Durham, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Knoxville, TN - Durham, NC, US

  1. What's the distance between Knoxville and Durham by coach?

    The distance between Knoxville and Durham by coach is approximately 281 miles (453 km).

  2. What is the best way to go from Knoxville to Durham without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/06
No data
19/06
No data
Today
US$73
21/06
US$95
22/06
US$113
23/06
US$85
24/06
US$85
25/06
No data
busbud logoThe cheapest trip from Knoxville to Durham was searched and found on 20 Jun 2025 with a price of US$73

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville to Durham as early as possible.

You can expect to pay from US$73 to US$113 for a bus ticket from Knoxville to Durham based on the last 2 days. You can expect to find the cheapest price for the trip at US$85, which is on 2025-06-23.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Durham but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Knoxville to Durham, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Knoxville to Durham that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Knoxville by bus?

Bus from Knoxville to Durham

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