Find coaches from Indianapolis to San Diego, CA, US

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Previously seen journeys

One passenger / one way

  • Departure time: 9 December at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 12 December at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 9 December at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 12 December at
    Destination city: San Diego
    Destination location: 5716 Hardy Ave
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 9 December at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 12 December at
    Destination city: San Diego
    Destination location: Balboa Park
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 9 December at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 12 December at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 9 December at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 12 December at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:

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Compare 2 ways to travel from Indianapolis to San Diego

Bus
Average priceUS$153 - US$476Average duration2d 12h
72kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$207 - US$346Average duration2d 9h
262kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Indianapolis to San Diego

Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 2 days, 9 hours 53 minutes and with fares starting at just US$207, it presents an excellent value for a comfortable ride.

2train per day
2d 9hAverage duration
US$207Cheapest ticket
262kgCO₂ emissions

Bus Indianapolis to San Diego, CA, US: Trip Overview

Average ticket priceUS$258
Average bus trip duration2d 12h
Number of daily buses20
Earliest bus departure03:30
Distance1782 miles
Latest bus departure23:30

Indianapolis to San Diego Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Indianapolis to San Diego from the most reliable bus companies operating this trip.

Discover how much the bus trip from Indianapolis to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Indianapolis - San Diego, CA, US

  1. What's the distance between Indianapolis and San Diego by coach?

    The distance between Indianapolis and San Diego by coach is approximately 1783 miles (2876 km).

  2. What is the best way to go from Indianapolis to San Diego without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/09
US$287
02/09
No data
Today
No data
04/09
No data
05/09
No data
06/09
No data
07/09
No data
08/09
US$148
busbud logoThe cheapest trip from Indianapolis to San Diego, CA, US was searched and found on 8 Sept 2025 with a price of US$148

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to San Diego, CA, US as early as possible.

You can expect to pay from US$148 to US$287 for a bus ticket from Indianapolis to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$148, which is on 2025-09-08.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to San Diego, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Indianapolis to San Diego will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Indianapolis to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Indianapolis by bus?

Bus from San Diego, CA, US to Indianapolis

You can also go to San Diego, CA, US by train

Train from Indianapolis to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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