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Compare 2 ways to go from Indianapolis to San Diego
Busbud recommends taking the train from Indianapolis to San DiegoAmong the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 2 days, 9 hours 53 minutes, and with fares starting at just US$207, it presents an excellent value for a comfortable ride.
Bus Indianapolis to San Diego, CA, US: Trip Overview
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Indianapolis to San Diego Bus
With Busbud, comparing and booking tickets for a bus from Indianapolis to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Indianapolis to San Diego from the most reliable bus companies operating this trip.
Discover how much the bus trip from Indianapolis to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Indianapolis and San Diego?
Frequently asked questions on the trip Indianapolis - San Diego, CA, US
What is the distance between Indianapolis and San Diego?
It's about 2876 km (1783 miles) from Indianapolis to San Diego.
What are the departure and arrival locations for buses traveling from Indianapolis to San Diego?
Buses traveling this route start their trip at Greyhound Amtrak Station, in Indianapolis, and end it at Mission Valley Sheraton, in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to San Diego, CA, US was searched and found on Sep 8, 2025 with a price of US$148To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to San Diego, CA, US, as early as possible.
You can expect to pay from US$148 to US$287 for a bus ticket from Indianapolis to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$148 which is on 2025-09-08.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Indianapolis to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to San Diego, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Indianapolis to San Diego will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Indianapolis to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top travelled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Indianapolis
Buses Leaving from Indianapolis
- Bus from Indianapolis to Muncie
- Bus Indianapolis - Nashville
- Indianapolis - Chicago
- Bus from Indianapolis to Bloomington
- Bus Indianapolis - Bloomington
- Indianapolis - Temple
- Bus from Indianapolis to St. Louis
- Bus Indianapolis - Columbus
- Indianapolis - Corpus Christi
- Bus from Indianapolis to Madison
- Bus Indianapolis - Detroit
- Indianapolis - Newark
- Bus from Indianapolis to Ashland
- Bus Indianapolis - South Bend
- Indianapolis - Burlington
Buses Going to Indianapolis
- Bus from South Bend to Indianapolis
- Bus Bloomington - Indianapolis
- Bloomington - Indianapolis
- Bus from Greenfield to Indianapolis
- Bus Merrillville - Indianapolis
- Terre Haute - Indianapolis
- Bus from Chicago to Indianapolis
- Bus St. Louis - Indianapolis
- Detroit - Indianapolis
- Bus from New York City to Indianapolis
- Bus Toledo - Indianapolis
- London - Indianapolis
- Bus from Buffalo to Indianapolis
- Bus Columbus - Indianapolis
- Peoria - Indianapolis
Popular Buses Connecting San Diego
Buses Leaving from San Diego
- Bus from San Diego to San Ysidro
- Bus San Diego - Lafayette
- San Diego - San Marcos
- Bus from San Diego to San Francisco
- Bus San Diego - Las Vegas
- San Diego - Las Vegas
- Bus from San Diego to Los Angeles
- Bus San Diego - Palm Springs
- San Diego - Temecula
- Bus from San Diego to Anaheim
- Bus San Diego - Calexico
- San Diego - Phoenix
- Bus from San Diego to Yuma
- Bus San Diego - Columbus
- San Diego - El Centro
Buses Going to San Diego
- Bus from Manchester to San Diego
- Bus Santa Fe - San Diego
- San Marcos - San Diego
- Bus from Grants to San Diego
- Bus Spring Hill - San Diego
- Seattle - San Diego
- Bus from Palm Springs to San Diego
- Bus Las Vegas - San Diego
- Anaheim - San Diego
- Bus from Yuma to San Diego
- Bus Phoenix - San Diego
- Willcox - San Diego
- Bus from San Francisco to San Diego
- Bus Calexico - San Diego
- Bakersfield - San Diego
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Albany - New York City
- Bus from Baton Rouge to New Orleans
- Bus Los Angeles - San Francisco
- Miami - Orlando
- Bus from Las Vegas to Los Angeles
- Bus Los Angeles - San Diego
- Atlanta - Savannah