Previously seen journeys
One passenger / one way
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Compare 2 ways to travel from Greenville to Jacksonville
Busbud recommends taking the bus from Greenville to JacksonvilleAmong the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 15 hours 35 minutes and with fares starting at just US$65, it presents an excellent value for a comfortable ride.
Bus Greenville, SC to Jacksonville, FL: Trip Overview
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Greenville to Jacksonville Bus
Busbud helps you find a bus from Greenville to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Greenville to Jacksonville.
Discover how much the bus trip from Greenville to Jacksonville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Greenville and Jacksonville?
Frequently asked questions on the trip Greenville, SC - Jacksonville, FL
How far is Jacksonville from Greenville by coach?
The distance between Greenville and Jacksonville by coach is approximately 315 miles (508 km).
Is there a way to reach Jacksonville from Greenville without flying?
You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Jacksonville, FL was searched and found on 4 Sept 2025 with a price of US$70To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Jacksonville, FL as early as possible.
You can expect to pay from US$70 to US$70 for a bus ticket from Greenville, SC to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at US$70, which is on 2025-09-04.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Jacksonville!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Greenville to Jacksonville.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Jacksonville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Jacksonville.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
What's the cheapest way to go from Greenville, SC to Jacksonville, FL?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Spartanburg
- Coach Greenville - Charleston
- Bus Greenville - Charleston
- Greenville - Greensboro
- Bus from Greenville to Miami
- Coach Greenville - Chicago
- Bus Greenville - Columbus
- Greenville - Oklahoma City
- Bus from Greenville to San Antonio
- Coach Greenville - New York City
- Bus Greenville - Atlanta
- Greenville - Anderson
- Bus from Greenville to Charlotte
- Coach Greenville - Lima
- Bus Greenville - Norcross
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Coach Burlington - Greenville
- Bus Nashville - Greenville
- Savannah - Greenville
- Bus from Knoxville to Greenville
- Coach Orlando - Greenville
- Bus Lima - Greenville
- Charlotte - Greenville
- Bus from Dublin to Greenville
- Coach Myrtle Beach - Greenville
- Bus Memphis - Greenville
- Spartanburg - Greenville
- Bus from Pittsburgh to Greenville
- Coach Durham - Greenville
- Bus Brunswick - Greenville
Popular Buses Connecting Jacksonville
Buses Leaving from Jacksonville
- Bus from Jacksonville to Jacksonville
- Coach Jacksonville - Miami
- Bus Jacksonville - Atlanta
- Jacksonville - Savannah
- Bus from Jacksonville to Gainesville
- Coach Jacksonville - Gainesville
- Bus Jacksonville - Gainesville
- Jacksonville - Orlando
- Bus from Jacksonville to Tampa
- Coach Jacksonville - New York City
- Bus Jacksonville - West Palm Beach
- Jacksonville - Henderson
- Bus from Jacksonville to Rocky Mount
- Coach Jacksonville - Charlotte
- Bus Jacksonville - Fort Pierce
Buses Going to Jacksonville
- Bus from Jacksonville to Jacksonville
- Coach Orlando - Jacksonville
- Bus Tampa - Jacksonville
- Miami - Jacksonville
- Bus from San Marcos to Jacksonville
- Coach Boston - Jacksonville
- Bus Wilson - Jacksonville
- Gainesville - Jacksonville
- Bus from Philadelphia to Jacksonville
- Coach New York City - Jacksonville
- Bus Atlanta - Jacksonville
- Moline - Jacksonville
- Bus from Lakeland to Jacksonville
- Coach New Orleans - Jacksonville
- Bus St. Petersburg - Jacksonville
Popular routes in this country
- Bus from Niagara Falls to New York City
- Coach Atlanta - Savannah
- Bus Philadelphia - New York City
- Tallahassee - Panama City
- Bus from Houston to Dallas
- Coach Baton Rouge - New Orleans
- Bus Las Vegas - Los Angeles
- Chicago - Cleveland
- Bus from New York City to Niagara Falls
- Coach Washington - Baltimore
- Bus Dallas - Houston
- Atlanta - Nashville
- Bus from Baltimore to New York City
- Coach Orlando - Fort Lauderdale
- Bus New York City - Baltimore