Bus Tickets from Knoxville, TN to Roanoke

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TodayJun 23
TomorrowJun 24
WedJun 25
from US$45
ThuJun 26
FriJun 27
SatJun 28
from US$47
SunJun 29
MonJun 30

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 25 at
    Departure city: Knoxville
    Departure location: Knoxville Bus Station
    Arrival time: June 26 at
    Destination city: Roanoke
    Destination location: Roanoke Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 5:23 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Bus Knoxville to Roanoke: Trip Overview

Average Ticket PriceUS$48
Average Bus Trip Duration5h 5m
Number of daily buses1
Earliest bus departure10:35pm
Distance378 km
Latest bus departure10:50pm

Knoxville to Roanoke Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Roanoke.

We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Roanoke.

Whether it is cheap bus tickets or more luxurious buses going to Roanoke from Knoxville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Knoxville, TN - Roanoke

  1. How far is Knoxville from Roanoke?

    It's about 385 km (239 miles) from Knoxville to Roanoke.

  2. What are the departure and arrival locations for buses traveling from Knoxville to Roanoke?

    Buses departing from 100 Kirkwood St in Knoxville will take you to Salem - Exit 140 Park & Ride in Roanoke.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-21
US$40
06-22
No data
Today
No data
06-24
No data
06-25
US$37
06-26
No data
06-27
No data
06-28
US$39
busbud logoThe cheapest trip from Knoxville to Roanoke was searched and found on Jun 25, 2025 with a price of US$37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville to Roanoke, as early as possible.

You can expect to pay from US$37 to US$40 for a bus ticket from Knoxville to Roanoke based on the last 2 days. You can expect to find the cheapest price for the trip at US$37 which is on 2025-06-25.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Roanoke but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Knoxville to Roanoke.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Roanoke.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Roanoke.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Knoxville by bus?

Bus from Knoxville to Roanoke

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