Bus Tickets from Cleveland, OH, US to Knoxville, TN

Next departures

Next departures for Cleveland to Knoxville on September 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Cleveland Bus Station
Knoxville Bus StationCheapest
Greyhound Lines, Inc.
Cleveland Bus Station
Knoxville Bus StationFastest
Greyhound Lines, Inc.
Cleveland Bus Station
Knoxville Bus StationNo tags

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Bus Cleveland, OH, US to Knoxville, TN: Trip Overview

Average Ticket PriceUS$85
Average Bus Trip Duration16h 40m
Number of daily buses2
Earliest bus departure2:35am
Distance641 km
Latest bus departure5:20pm

Cleveland to Knoxville Bus

With Busbud, comparing and booking tickets for a bus from Cleveland to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Cleveland to Knoxville will be provided by the most trusted bus companies.

Discover how much the bus trip from Cleveland to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Cleveland, OH, US - Knoxville, TN

  1. How far is Cleveland from Knoxville?

    The distance between Cleveland and Knoxville is around 647 km (401 miles).

  2. What are the departure and arrival locations for buses traveling from Cleveland to Knoxville?

    Buses traveling this route start their trip at Greyhound Station, in Cleveland, and end it at 100 Kirkwood St, in Knoxville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-30
US$122
08-31
US$83
Today
US$106
09-02
US$84
09-03
US$72
09-04
No data
09-05
US$62
09-06
No data
busbud logoThe cheapest trip from Cleveland, OH, US to Knoxville, TN was searched and found on Sep 5, 2025 with a price of US$62

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cleveland, OH, US to Knoxville, TN, as early as possible.

You can expect to pay from US$62 to US$132 for a bus ticket from Cleveland, OH, US to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at US$62 which is on 2025-09-05.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Cleveland to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Cleveland to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Cleveland to Knoxville will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Cleveland to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Cleveland, OH, US by bus?

Bus from Knoxville, TN to Cleveland, OH, US

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