Bus Tickets from Popayán to Medellin

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TodayJul 18
from $58
TomorrowJul 19
from $29
SunJul 20
from $29
MonJul 21
from $29
TueJul 22
from $58
WedJul 23
ThuJul 24
from $24
FriJul 25

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 19 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: July 20 at
    Destination city: Medellin
    Destination location: Terminal del Sur
    Operated by: Coomotor + Bolivariano
    Coomotor + Bolivariano
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 19 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: July 20 at
    Destination city: Medellin
    Destination location: Terminal del Sur
    Operated by: Expreso Palmira + Bolivariano
    Expreso Palmira + Bolivariano
    Vehicle: BusDuration:
  • Departure time: July 19 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: July 20 at
    Destination city: Medellin
    Destination location: Terminal del Sur
    Operated by: Expreso Palmira + Bolivariano
    Expreso Palmira + Bolivariano
    Vehicle: BusDuration:
  • Departure time: July 19 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: July 20 at
    Destination city: Medellin
    Destination location: Terminal del Sur
    Operated by: Coomotor + Bolivariano
    Coomotor + Bolivariano
    Vehicle: BusDuration:
  • Departure time: July 19 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: July 20 at
    Destination city: Medellin
    Destination location: Terminal del Norte
    Operated by: Expreso Palmira + Rápido Tolima
    Expreso Palmira + Rápido Tolima
    Vehicle: BusDuration:

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Bus Popayán to Medellin: Trip Overview

Average ticket price$35
Average bus trip duration14h
Number of daily buses5
Earliest bus departure12:00am
Distance270 miles (434 km)
Latest bus departure11:00pm

Popayán to Medellin Bus

Busbud helps you find a bus from Popayán to Medellin. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Popayán to Medellin will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Medellin from Popayán, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Popayán - Medellin

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/16
No data
07/17
$34
Today
No data
07/19
No data
07/20
No data
07/21
No data
07/22
No data
07/23
No data
busbud logoThe cheapest trip from Popayán to Medellin was searched and found on Jul 17, 2025 with a price of $34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Popayán to Medellin, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Popayán and Medellin!

Much more than a mere vehicle taking you from Popayán to Medellin, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Popayán to Medellin.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Popayán to Medellin.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Popayán by bus?

Bus from Popayán to Medellin

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