Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal del Sur | Terminal Popayan | CheapestFastest | |||||
 | Terminal del Sur | Terminal Popayan | No tags | |||||
Bolivariano + Expreso Gaitana | Terminal del Sur | Terminal Popayan | No tags | |||||
Bolivariano + Flota Magdalena | Terminal del Sur | Terminal Popayan | No tags | |||||
Bolivariano + Expreso Gaitana | Terminal del Sur | Terminal Popayan | No tags |
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Bus Medellin to Popayán: Trip Overview
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Medellin to Popayán Bus
With Busbud, comparing and booking tickets for a bus from Medellin to Popayán is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Medellin to Popayán from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Medellin to Popayán, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Medellin and Popayán?
Frequently asked questions for your trip Medellin - Popayán
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Medellin to Popayán was searched and found on Aug 26, 2025 with a price of $25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Medellin to Popayán, as early as possible.
You can expect to pay from $25 to $34 for a bus ticket from Medellin to Popayán based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2025-08-26.
Usually Lineas Pereiranas will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Medellin to Popayán.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Medellin to Popayán, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Medellin to Popayán that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Medellin to Popayán, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top traveled bus routes
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Popular Buses Connecting Medellin
Buses Leaving from Medellin
- Bus from Medellin to Bucaramanga
- Bus Medellin - Montería
- Medellin - Manizales
- Bus from Medellin to Coveñas
- Bus Medellin - Caucasia
- Medellin - Covenas
- Bus from Medellin to Pereira
- Bus Medellin - Armenia
- Medellin - Necoclí
- Bus from Medellin to Santa Fe de Antioquia
- Bus Medellin - Cúcuta
- Medellin - Barranquilla
- Bus from Medellin to Palomino
- Bus Medellin - San Rafael
- Medellin - Ipiales
Buses Going to Medellin
- Bus from Montería to Medellin
- Bus Ibagué - Medellin
- Bucaramanga - Medellin
- Bus from Manizales to Medellin
- Bus Apartadó - Medellin
- Puerto Berrío - Medellin
- Bus from Guatape to Medellin
- Bus Barranquilla - Medellin
- Necoclí - Medellin
- Bus from Cúcuta to Medellin
- Bus Santa Fe de Antioquia - Medellin
- Mompós - Medellin
- Bus from Neiva to Medellin
- Bus Popayán - Medellin
- San Onofre - Medellin
Popular Buses Connecting Popayán
Buses Leaving from Popayán
Buses Going to Popayán
- Bus from Cali to Popayán
- Bus Bogotá - Popayán
- Pitalito - Popayán
- Bus from Pereira to Popayán
- Bus Bucaramanga - Popayán
- San Agustín - Popayán
- Bus from Medellin to Popayán
- Bus Neiva - Popayán
- Ipiales - Popayán
- Bus from La Plata to Popayán
- Bus Florencia - Popayán
- Campoalegre - Popayán
- Bus from Hobo to Popayán
- Bus Tesalia - Popayán
- Cúcuta - Popayán
Popular routes in this country
- Bus from Medellin to Jardin
- Bus Medellin - Guatape
- Cartagena - Medellin
- Bus from Santa Marta to Medellin
- Bus Jardin - Medellin
- Bogotá - Cali
- Bus from Cali to Medellin
- Bus Armenia - Bogotá
- Pereira - Medellin
- Bus from Bogotá to San Gil
- Bus Armenia - Medellin
- Cali - Bogotá
- Bus from Cartagena to Barranquilla
- Bus Cartagena - Palomino
- Bogotá - Villa de Leyva