Find coaches from Popayán to Medellín, CO

Find affordable coach tickets from Popayán to Medellín, CO with flexible options. Book your journey now

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Fri27 Jun
from US$26
Sat28 Jun
from US$26
Sun29 Jun
from US$26
Mon30 Jun
from US$25
Tue1 Jul
Wed2 Jul
Thu3 Jul
Fri4 Jul

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 28 June at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: 29 June at
    Destination city: Medellín
    Destination location: Terminal del Norte
    Operated by: BolivarianoBolivariano
    Vehicle: BusDuration:
  • Departure time: 28 June at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: 29 June at
    Destination city: Medellín
    Destination location: Terminal del Sur
    Operated by: Lineas PereiranasLineas Pereiranas
    Vehicle: BusDuration:
  • Departure time: 28 June at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: 29 June at
    Destination city: Medellín
    Destination location: Terminal del Norte
    Operated by: Expreso Palmira + Rápido Tolima
    Expreso Palmira + Rápido Tolima
    Vehicle: BusDuration:
  • Departure time: 28 June at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: 29 June at
    Destination city: Medellín
    Destination location: Terminal del Norte
    Operated by: Continental Bus + Rápido Ochoa
    Continental Bus + Rápido Ochoa
    Vehicle: BusDuration:
  • Departure time: 28 June at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: 29 June at
    Destination city: Medellín
    Destination location: Terminal del Norte
    Operated by: Continental Bus + Rápido Tolima
    Continental Bus + Rápido Tolima
    Vehicle: BusDuration:

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Bus Popayán to Medellín: Trip Overview

Average ticket priceUS$35
Average bus trip duration14h 11m
Number of daily buses4.709677419354838
Earliest bus departure00:00
Distance274 miles
Latest bus departure23:00

Popayán to Medellín Bus

Busbud helps you find a bus from Popayán to Medellín. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Popayán to Medellín will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Medellín from Popayán, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Popayán - Medellín, CO

  1. What's the distance between Popayán and Medellín by coach?

    The distance between Popayán and Medellín by coach is approximately 271 miles (437 km).

  2. How can I travel from Popayán to Medellín avoiding air travel?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
23/06
US$33
24/06
No data
Today
US$33
26/06
US$25
27/06
US$33
28/06
US$25
29/06
US$25
30/06
US$24
busbud logoThe cheapest trip from Popayán to Medellín was searched and found on 30 Jun 2025 with a price of US$24

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Popayán to Medellín as early as possible.

You can expect to pay from US$24 to US$33 for a bus ticket from Popayán to Medellín based on the last 2 days. You can expect to find the cheapest price for the trip at US$24, which is on 2025-06-30.

Usually Lineas Pereiranas will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Popayán and Medellín!

Much more than a mere vehicle taking you from Popayán to Medellín, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Popayán to Medellín.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Popayán to Medellín.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Popayán by bus?

Bus from Popayán to Medellín

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