Find coaches from Winston-Salem to Chicago

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Previously seen journeys

One passenger / one way

  • Departure time: 15 September at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: 16 September at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 15 September at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: 16 September at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 15 September at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: 16 September at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 15 September at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: 16 September at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 15 September at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: 16 September at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Winston-Salem to Chicago: Trip Overview

Average ticket priceUS$127
Average bus trip duration1d 2h
Number of daily buses9
Earliest bus departure06:55
Distance562 miles
Latest bus departure18:15

Winston-Salem to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Winston-Salem to Chicago.

Bus service from Winston-Salem to Chicago will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from Winston-Salem, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Winston-Salem - Chicago

  1. How far is Chicago from Winston-Salem by coach?

    The journey from Winston-Salem to Chicago by coach covers an approximate distance of 562 miles (906 km).

  2. What is the best way to go from Winston-Salem to Chicago without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/08
No data
01/09
US$122
Today
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03/09
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04/09
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05/09
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06/09
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07/09
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busbud logoThe cheapest trip from Winston-Salem to Chicago was searched and found on 1 Sept 2025 with a price of US$122

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Chicago as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Winston-Salem to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Winston-Salem to Chicago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Winston-Salem to Chicago.

Tune out to the fine sounds of your best music playlist on your bus trip from Winston-Salem to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Winston-Salem by bus?

Bus from Chicago to Winston-Salem

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