Bus Tickets from Winston-Salem to Chicago

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Previously seen trips

One passenger / one way

  • Departure time: September 15 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: September 16 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 15 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: September 16 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 15 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: September 16 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 15 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: September 16 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 15 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: September 16 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Winston-Salem to Chicago: Trip Overview

Average Ticket PriceUS$130
Average Bus Trip Duration1d 2h
Number of daily buses10
Earliest bus departure6:55am
Distance893 km
Latest bus departure6:15pm

Winston-Salem to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Winston-Salem to Chicago.

Bus service from Winston-Salem to Chicago will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from Winston-Salem, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Winston-Salem - Chicago

  1. What is the distance between Winston-Salem and Chicago?

    It's about 906 km (562 miles) from Winston-Salem to Chicago.

  2. What are the departure and arrival locations for buses traveling from Winston-Salem to Chicago?

    Buses departing from Winston Salem Greyhound Bus Station in Winston-Salem will take you to Downtown Greyhound Station in Chicago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-31
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09-01
US$122
Today
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09-03
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busbud logoThe cheapest trip from Winston-Salem to Chicago was searched and found on Sep 1, 2025 with a price of US$122

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Chicago, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Winston-Salem to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Winston-Salem to Chicago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Winston-Salem to Chicago.

Tune out to the fine sounds of your best music playlist on your bus trip from Winston-Salem to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Winston-Salem by bus?

Bus from Chicago to Winston-Salem

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