Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Winston Salem Greyhound Bus Station | Pittsburgh Intermodal Station | Cheapest | ||||
 | Bus | Winston Salem Greyhound Bus Station | Pittsburgh Intermodal Station | Fastest | ||||
| Bus | Winston Salem Greyhound Bus Station | Pittsburgh Intermodal Station | No tags |
Last refresh of the prices: Yesterday at 3:44 PM EST.
Get from Winston-Salem to Pittsburgh
The journey takes about 17 hours 40 minutes, and with fares starting at just $149, it presents an excellent value for a comfortable ride.
Where are the popular stops in Winston-Salem and Pittsburgh?
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Compare bus companies
Based on 87495 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $150
Frequently asked questions about travelling from Winston-Salem to Pittsburgh by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Winston-Salem to Pittsburgh?
The cheapest bus tickets from Winston-Salem to Pittsburgh start from $149. The average price for this route is around $207. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Winston-Salem to Pittsburgh?
The average bus travel time from Winston-Salem to Pittsburgh is 17h 40m, covering a distance of 484 km. The quickest bus can get you there in 15h 35m and is operated by Greyhound.
Which bus companies service the Winston-Salem to Pittsburgh route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Winston-Salem to Pittsburgh?
The earliest bus departs from Winston-Salem to Pittsburgh at 7:10am. And the latest bus departs at 6:15pm.
What are the CO₂ emissions for the bus trip from Winston-Salem to Pittsburgh?
A bus trip from Winston-Salem to Pittsburgh generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Winston-Salem to Pittsburgh was searched and found on Jan 11, 2026 with a price of $146To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Pittsburgh, as early as possible.
You can expect to pay from $146 to $265 for a bus ticket from Winston-Salem to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $157 which is on 2026-01-17.
