Find coaches from St. Louis to Winston-Salem

Bus St. Louis to Winston-Salem: Trip Overview

Average ticket priceUS$181
Average bus trip duration22h
Number of daily buses4
Earliest bus departure01:40
Distance573 miles
Latest bus departure23:30

St. Louis to Winston-Salem Bus

With Busbud, comparing and booking tickets for a bus from St. Louis to Winston-Salem is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from St. Louis to Winston-Salem from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Winston-Salem from St. Louis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip St. Louis - Winston-Salem

  1. What's the distance between St. Louis and Winston-Salem by coach?

    The journey from St. Louis to Winston-Salem by coach covers an approximate distance of 573 miles (924 km).

  2. How can I travel from St. Louis to Winston-Salem avoiding air travel?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/07
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30/07
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Today
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01/08
US$77
02/08
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03/08
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04/08
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05/08
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busbud logoThe cheapest trip from St. Louis to Winston-Salem was searched and found on 1 Aug 2025 with a price of US$77

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Winston-Salem as early as possible.

You can expect to pay from US$77 to US$93 for a bus ticket from St. Louis to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$77, which is on 2025-08-01.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from St. Louis to Winston-Salem.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Louis to Winston-Salem, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St. Louis to Winston-Salem.

Tune out to the fine sounds of your best music playlist on your bus trip from St. Louis to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to St. Louis by bus?

Bus from St. Louis to Winston-Salem

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