Next departures to Santa Clara
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: 31 July atDeparture city: San Luis ObispoDeparture location: Cal Poly Vista Grande Dining ComplexArrival time: 31 July atDestination city: Santa ClaraDestination location: Santa Ana Regional Transportation CenterOperated by: Amtrak
Vehicle: BusDuration: - Departure time: 31 July atDeparture city: San Luis ObispoDeparture location: AMTRAK StationArrival time: 1 August atDestination city: Santa ClaraDestination location: Santa Ana Regional Transportation CenterOperated by: AmtrakVehicle: BusDuration:
- Departure time: 31 July atDeparture city: San Luis ObispoDeparture location: Cal Poly Vista Grande Dining ComplexArrival time: 1 August atDestination city: Santa ClaraDestination location: Santa Ana Regional Transportation CenterOperated by: AmtrakVehicle: BusDuration:
- Departure time: 31 July atDeparture city: San Luis ObispoDeparture location: Cal Poly Vista Grande Dining ComplexArrival time: 31 July atDestination city: Santa ClaraDestination location: Santa Ana Regional Transportation CenterOperated by: AmtrakVehicle: BusDuration:
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Compare 2 ways to travel from San Luis Obispo to Santa Clara
Busbud recommends taking the bus from San Luis Obispo to Santa ClaraAmong the sustainable travel choices, the bus stands out as a good way to reach Santa Clara. The journey takes about 8 hours 15 minutes and with fares starting at just US$76, it presents an excellent value for a comfortable ride.
Bus San Luis Obispo to Santa Clara, US: Trip Overview
Compare bus companies
Based on 5352 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$76
San Luis Obispo to Santa Clara Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Luis Obispo to Santa Clara.
We make it our job to connect you with the most dependable bus companies that cover bus service from San Luis Obispo to Santa Clara.
Discover how much the bus trip from San Luis Obispo to Santa Clara will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip San Luis Obispo - Santa Clara, US
What's the distance between San Luis Obispo and Santa Clara by coach?
The distance between San Luis Obispo and Santa Clara by coach is approximately 164 miles (264 km).
What is the best way to go from San Luis Obispo to Santa Clara without a car?
You can travel to Santa Clara from San Luis Obispo by coach, which provides a smooth ride and an affordable and convenient trip. Depending on your preferences, another alternative is to explore ridesharing trips.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Luis Obispo to Santa Clara, US was searched and found on 29 Jul 2025 with a price of US$53To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to Santa Clara, US as early as possible.
You can expect to pay from US$53 to US$99 for a bus ticket from San Luis Obispo to Santa Clara, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$53, which is on 2025-08-04.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Luis Obispo to Santa Clara but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Luis Obispo to Santa Clara.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Luis Obispo to Santa Clara will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from San Luis Obispo to Santa Clara while indulging in miles on end of beautiful scenic views.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
What's the cheapest way to go from San Luis Obispo to Santa Clara, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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