Find coaches from San Diego (CA), US to Santa Clara (CA), US

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Today31 May
from US$107
Tomorrow1 Jun
Mon2 Jun
Tue3 Jun
Wed4 Jun
Thu5 Jun
Fri6 Jun
Sat7 Jun

Next departures to Santa Clara

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 31 May at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: 1 June at
    Destination city: Santa Clara
    Destination location: Great America Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: 31 May at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: 1 June at
    Destination city: Santa Clara
    Destination location: Santa Clara Transit Center
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

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Compare 2 ways to travel from San Diego to Santa Clara

Bus
Average priceUS$115 - US$117Average duration14h 22m
17kg CO₂e5 out of 5 stars
Train
Average priceUS$37 - US$47Average duration2h 29m
12kg CO₂e1 out of 5 stars
CheapestFastestMost eco-friendly
busbud logoBusbud recommends taking the train from San Diego to Santa Clara

Among the sustainable travel choices, the train stands out as a good way to reach Santa Clara. The journey takes about 2 hours 29 minutes and with fares starting at just US$37, it presents an excellent value for a comfortable ride.

6train per day
2h 29mAverage duration
US$37Cheapest ticket
12kgCO₂ emissions

Bus San Diego to Santa Clara: Trip Overview

Average ticket priceUS$115
Average bus trip duration14h 22m
Number of daily buses2
Earliest bus departure20:45
Distance422 miles
Latest bus departure21:25

San Diego to Santa Clara Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Santa Clara is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from San Diego to Santa Clara will be provided by the most trusted bus companies.

Discover how much the bus trip from San Diego to Santa Clara will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Diego (CA), US - Santa Clara (CA), US

  1. How much does it cost to go to Santa Clara by bus?

    Coach ticket prices from San Diego to Santa Clara can start as low as US$115, though the average price for this trip is US$115. The exact cost can vary based on different factors such as the time of travel, the day of the week, and the coach service provider. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long is a coach from San Diego to Santa Clara?

    The coach journey between San Diego and Santa Clara lasts about 14h 22m. If you're looking for the fastest trip, you can get there in just about 14h 14m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from San Diego to Santa Clara?

    The first coach from San Diego to Santa Clara leaves at 20:45. Times and services may vary during weekends and holidays.

  4. What's the distance between San Diego and Santa Clara by coach?

    The journey from San Diego to Santa Clara by coach covers an approximate distance of 420 miles (677 km).

  5. What is the best way to go from San Diego to Santa Clara without flying?

    To travel from San Diego to Santa Clara without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

  6. Can I catch a night bus from San Diego to Santa Clara?

    You can hop on buses departing from San Diego until 21:25 and reaching Santa Clara the following day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/05
US$108
30/05
US$102
Today
US$102
01/06
US$108
02/06
US$108
03/06
US$108
04/06
US$108
05/06
US$108
busbud logoThe cheapest trip from San Diego to Santa Clara was searched and found on 30 May 2025 with a price of US$102

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Santa Clara as early as possible.

You can expect to pay from US$102 to US$108 for a bus ticket from San Diego to Santa Clara based on the last 2 days. You can expect to find the cheapest price for the trip at US$108, which is on 2025-06-01.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Diego to Santa Clara.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from San Diego to Santa Clara, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Diego to Santa Clara will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from San Diego to Santa Clara, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to San Diego by bus?

Bus from San Diego to Santa Clara

You can also go to Santa Clara by train

Train from San Diego to Santa Clara

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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