Next departures to Santa Clara
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: 17 July atDeparture city: San DiegoDeparture location: Santa Fe DepotArrival time: 18 July atDestination city: Santa ClaraDestination location: Great America StationOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: 17 July atDeparture city: San DiegoDeparture location: Santa Fe DepotArrival time: 18 July atDestination city: Santa ClaraDestination location: Santa Clara Transit CenterOperated by: AmtrakVehicle: BusDuration:
- Departure time: 17 July atDeparture city: San DiegoDeparture location: Santa Fe DepotArrival time: 18 July atDestination city: Santa ClaraDestination location: Santa Clara Transit CenterOperated by: AmtrakVehicle: BusDuration:
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Compare 2 ways to travel from San Diego to Santa Clara
Busbud recommends taking the train from San Diego to Santa ClaraAmong the sustainable travel choices, the train stands out as a good way to reach Santa Clara. The journey takes about 1 hour 54 minutes and with fares starting at just US$32, it presents an excellent value for a comfortable ride.
Bus San Diego to Santa Clara: Trip Overview
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Based on 5301 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$115
San Diego to Santa Clara Bus
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Bus service from San Diego to Santa Clara will be provided by the most trusted bus companies.
Discover how much the bus trip from San Diego to Santa Clara will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip San Diego, CA, US - Santa Clara, US
What's the distance between San Diego and Santa Clara by coach?
The journey from San Diego to Santa Clara by coach covers an approximate distance of 420 miles (677 km).
What is the best way to go from San Diego to Santa Clara without flying?
To travel from San Diego to Santa Clara without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego to Santa Clara was searched and found on 21 Jul 2025 with a price of US$29To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Santa Clara as early as possible.
You can expect to pay from US$29 to US$169 for a bus ticket from San Diego to Santa Clara based on the last 2 days. You can expect to find the cheapest price for the trip at US$29, which is on 2025-07-21.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from San Diego to Santa Clara.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from San Diego to Santa Clara, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Diego to Santa Clara will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Make a music playlist for your bus ride from San Diego to Santa Clara, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top travelled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting San Diego
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Buses Going to San Diego
Popular Buses Connecting Santa Clara
Buses Leaving from Santa Clara
- Bus from Santa Clara to San Jose
- Coach Santa Clara - Santa Barbara
- Bus Santa Clara - Fremont
- Santa Clara - San Francisco
- Bus from Santa Clara to Orlando
- Coach Santa Clara - Berkeley
- Bus Santa Clara - Chicago
- Santa Clara - Chico
- Bus from Santa Clara to Elk Grove
- Coach Santa Clara - San Juan Capistrano
- Bus Santa Clara - Solana Beach
- Santa Clara - San Diego
Buses Going to Santa Clara
- Bus from San Francisco to Santa Clara
- Coach Eugene - Santa Clara
- Bus Sacramento - Santa Clara
- San Diego - Santa Clara
- Bus from St. Louis to Santa Clara
- Coach Fremont - Santa Clara
- Bus Los Angeles - Santa Clara
- Santa Barbara - Santa Clara
- Bus from Moorpark to Santa Clara
- Coach Santa Cruz - Santa Clara
- Bus Las Vegas - Santa Clara
- Yosemite National Park - Santa Clara
- Bus from Paso Robles to Santa Clara