Find coaches from San Carlos, CL to Santiago, CL

Find affordable coach tickets from San Carlos, CL to Santiago, CL with flexible options. Book your journey now

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Today20 Jun
Tomorrow21 Jun
from US$16
Sun22 Jun
from US$16
Mon23 Jun
from US$19
Tue24 Jun
from US$15
Wed25 Jun
Thu26 Jun
Fri27 Jun

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 21 June at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 21 June at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:

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Bus San Carlos to Santiago: Trip Overview

Average ticket priceUS$15
Average bus trip duration3h 57m
Number of daily buses16.703703703703702
Earliest bus departure00:10
Distance217 miles
Latest bus departure19:35

San Carlos to Santiago Bus

With Busbud, comparing and booking tickets for a bus from San Carlos to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Carlos to Santiago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from San Carlos to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Carlos, CL - Santiago, CL

  1. What's the distance between San Carlos and Santiago by coach?

    The journey from San Carlos to Santiago by coach covers an approximate distance of 222 miles (358 km).

  2. What is the best way to go from San Carlos to Santiago without a car?

    You can reach Santiago from San Carlos by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/06
US$12
19/06
US$14
Today
US$18
21/06
US$15
22/06
US$15
23/06
US$18
24/06
US$14
25/06
No data
busbud logoThe cheapest trip from San Carlos to Santiago was searched and found on 18 Jun 2025 with a price of US$12

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Carlos to Santiago as early as possible.

You can expect to pay from US$12 to US$30 for a bus ticket from San Carlos to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at US$14, which is on 2025-06-24.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Carlos to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Carlos to Santiago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Carlos to Santiago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Carlos to Santiago.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to San Carlos by bus?

Bus from San Carlos to Santiago

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