Find coaches from Calama to Santiago, CL

Find affordable coach tickets from Calama to Santiago, CL with flexible options. Book your journey now

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Today20 Jun
from US$58
Tomorrow21 Jun
from US$40
Sun22 Jun
from US$42
Mon23 Jun
from US$40
Tue24 Jun
from US$42
Wed25 Jun
from US$40
Thu26 Jun
from US$40
Fri27 Jun
from US$40

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 21 June at
    Departure city: Calama
    Departure location: Terminal de buses Calama
    Arrival time: 22 June at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja - San Francisco de Borja
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 21 June at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: 22 June at
    Destination city: Santiago
    Destination location: San Borja
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: Calama
    Departure location: Calama
    Arrival time: 22 June at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja - San Francisco de Borja
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: 22 June at
    Destination city: Santiago
    Destination location: San Borja
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: Calama
    Departure location: Calama
    Arrival time: 22 June at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja
    Operated by: AndimarAndimar
    Vehicle: BusDuration:

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Bus Calama to Santiago: Trip Overview

Average ticket priceUS$47
Average bus trip duration22h
Number of daily buses22.323943661971835
Earliest bus departure08:30
Distance766 miles
Latest bus departure22:50

Calama to Santiago Bus

Busbud helps you find a bus from Calama to Santiago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Calama to Santiago will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santiago from Calama, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Calama - Santiago, CL

  1. How far is Santiago from Calama by coach?

    The distance between Calama and Santiago by coach is approximately 764 miles (1232 km).

  2. What is the best way to go from Calama to Santiago without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/06
US$49
19/06
US$54
Today
US$40
21/06
US$38
22/06
US$40
23/06
US$38
24/06
US$40
25/06
US$38
busbud logoThe cheapest trip from Calama to Santiago was searched and found on 21 Jun 2025 with a price of US$38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Calama to Santiago as early as possible.

You can expect to pay from US$38 to US$57 for a bus ticket from Calama to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at US$38, which is on 2025-06-21.

Usually PlussChile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Calama and Santiago!

Much more than a mere vehicle taking you from Calama to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Calama to Santiago.

Make a music playlist for your bus ride from Calama to Santiago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Calama by bus?

Bus from Calama to Santiago

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