Find coaches from Florence, SC, US to Greenville, SC

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Previously seen journeys

One passenger / one way

  • Departure time: 2 December at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: 3 December at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 7 December at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: 7 December at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 7 December at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: 8 December at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 2 January at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: 2 January at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 2 January at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: 3 January at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Compare 2 ways to travel from Florence to Greenville

Bus
Average priceUS$92 - US$198Average duration16h 10m
6kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$153 - US$375Average duration18h 30m
23kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Florence to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 16 hours 10 minutes and with fares starting at just US$92, it presents an excellent value for a comfortable ride.

4bus per day
16h 10mAverage duration
US$92Cheapest ticket
6kgCO₂ emissions

Bus Florence, SC, US to Greenville, SC: Trip Overview

Average ticket priceUS$128
Average bus trip duration16h 10m
Number of daily buses4
Earliest bus departure00:05
Distance151 miles
Latest bus departure16:15

Florence to Greenville Bus

With Busbud, comparing and booking tickets for a bus from Florence to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Greenville.

Discover how much the bus trip from Florence to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Florence, SC, US - Greenville, SC

  1. How far is Greenville from Florence by coach?

    The journey from Florence to Greenville by coach covers an approximate distance of 163 miles (263 km).

  2. What is the best way to go from Florence to Greenville without a car?

    The best way to go from Florence to Greenville without a car is by coach. They are frequent and reliable, offering a convenient and eco-friendly journey. Depending on your preferences, carpooling can also be considered as an option.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/09
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02/09
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Today
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04/09
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05/09
US$93
06/09
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07/09
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08/09
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busbud logoThe cheapest trip from Florence, SC, US to Greenville, SC was searched and found on 5 Sept 2025 with a price of US$93

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Greenville, SC as early as possible.

You can expect to pay from US$93 to US$93 for a bus ticket from Florence, SC, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$93, which is on 2025-09-05.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Florence to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Greenville.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Florence to Greenville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Greenville.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Florence, SC, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Greenville, SC to Florence, SC, US

You can also go to Greenville, SC by train

Train from Florence, SC, US to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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