Find coaches from Detroit, MI to Des Moines

Next departures

Next departures from Detroit to Des Moines on 23 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Detroit Bus Station
Des Moines (Subway)CheapestFastest

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Bus Detroit, MI to Des Moines: Trip Overview

Average ticket priceUS$87
Average bus trip duration16h 10m
Number of daily buses1
Earliest bus departure23:25
Distance543 miles

Detroit to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Detroit to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Detroit to Des Moines from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Detroit to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Detroit, MI - Des Moines

  1. What's the distance between Detroit and Des Moines by coach?

    The distance between Detroit and Des Moines by coach is approximately 545 miles (878 km).

  2. How can I travel from Detroit to Des Moines avoiding air travel?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/09
No data
19/09
US$79
Today
No data
21/09
No data
22/09
No data
23/09
US$68
24/09
US$68
25/09
US$99
busbud logoThe cheapest trip from Detroit, MI to Des Moines was searched and found on 23 Sept 2025 with a price of US$68

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Des Moines as early as possible.

You can expect to pay from US$68 to US$99 for a bus ticket from Detroit, MI to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$68, which is on 2025-09-23.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Detroit to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Des Moines, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Des Moines that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Detroit to Des Moines.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Detroit, MI by bus?

Bus from Des Moines to Detroit, MI

Why choose Busbud?

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