Bus Tickets from Detroit, MI to Des Moines

Next departures

Next departures for Detroit to Des Moines on September 23
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Detroit Bus Station
Des Moines (Subway)CheapestFastest

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Detroit, MI to Des Moines: Trip Overview

Average Ticket PriceUS$87
Average Bus Trip Duration16h 10m
Number of daily buses1
Earliest bus departure11:25pm
Distance875 km

Detroit to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Detroit to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Detroit to Des Moines from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Detroit to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Detroit, MI - Des Moines

  1. How far is Detroit from Des Moines?

    The distance between Detroit and Des Moines is around 878 km (545 miles).

  2. What are the departure and arrival locations for buses traveling from Detroit to Des Moines?

    Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Jefferson/Trailways Depot, in Des Moines.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-19
US$79
09-20
No data
Today
No data
09-22
No data
09-23
US$68
09-24
US$68
09-25
US$99
09-26
US$104
busbud logoThe cheapest trip from Detroit, MI to Des Moines was searched and found on Sep 23, 2025 with a price of US$68

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Des Moines, as early as possible.

You can expect to pay from US$68 to US$104 for a bus ticket from Detroit, MI to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$68 which is on 2025-09-23.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Detroit to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Des Moines, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Des Moines that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Detroit to Des Moines.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Detroit, MI by bus?

Bus from Des Moines to Detroit, MI

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