Find coaches from Columbus, OH to St. Louis

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Today1 Sept
from US$76
Tomorrow2 Sept
from US$54
Wed3 Sept
from US$63
Thu4 Sept
from US$52
Fri5 Sept
from US$52
Sat6 Sept
from US$52
Sun7 Sept
from US$57
Mon8 Sept

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 2 September at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 2 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 2 September at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 3 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 2 September at
    Departure city: Columbus
    Departure location: 100 E Rich St
    Arrival time: 2 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 2 September at
    Departure city: Columbus
    Departure location: 100 E Rich St
    Arrival time: 3 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 2 September at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 2 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Columbus, OH to St. Louis: Trip Overview

Average ticket priceUS$70
Average bus trip duration11h 30m
Number of daily buses5
Earliest bus departure04:50
Distance396 miles
Latest bus departure23:30

Columbus to St. Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Columbus to St. Louis.

Bus service from Columbus to St. Louis will be provided by the most trusted bus companies.

Discover how much the bus trip from Columbus to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Columbus, OH - St. Louis

  1. What's the distance between Columbus and St. Louis by coach?

    The distance between Columbus and St. Louis by coach is approximately 396 miles (638 km).

  2. How can I travel from Columbus to St. Louis avoiding air travel?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/08
US$55
31/08
US$47
Today
US$68
02/09
US$46
03/09
US$55
04/09
US$44
05/09
US$44
06/09
US$44
busbud logoThe cheapest trip from Columbus, OH to St. Louis was searched and found on 4 Sept 2025 with a price of US$44

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to St. Louis as early as possible.

You can expect to pay from US$44 to US$141 for a bus ticket from Columbus, OH to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$44, which is on 2025-09-04.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Columbus to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Columbus to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Columbus to St. Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Columbus to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Columbus, OH by bus?

Bus from St. Louis to Columbus, OH

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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