Find coaches from Cincinnati to Greenville, SC

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Previously seen journeys

One passenger / one way

  • Departure time: 11 October at
    Departure city: Cincinnati
    Departure location: Cincinnati Bus Station
    Arrival time: 11 October at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 11 October at
    Departure city: Cincinnati
    Departure location: Cincinnati (Downtown)
    Arrival time: 12 October at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 11 October at
    Departure city: Cincinnati
    Departure location: Cincinnati Bus Station
    Arrival time: 12 October at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 11 October at
    Departure city: Cincinnati
    Departure location: Cincinnati Bus Station
    Arrival time: 12 October at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 8 November at
    Departure city: Cincinnati
    Departure location: Cincinnati Bus Station
    Arrival time: 8 November at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to travel from Cincinnati to Greenville

Bus
Average priceUS$79 - US$164Average duration19h
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$199 - US$250Average duration1d 1h
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Cincinnati to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 19 hours and with fares starting at just US$79, it presents an excellent value for a comfortable ride.

4bus per day
19hAverage duration
US$79Cheapest ticket
13kgCO₂ emissions

Bus Cincinnati to Greenville, SC: Trip Overview

Average ticket priceUS$108
Average bus trip duration19h
Number of daily buses4
Earliest bus departure00:55
Distance325 miles
Latest bus departure17:30

Cincinnati to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Cincinnati to Greenville.

We make sure you can find a bus service from Cincinnati to Greenville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Cincinnati, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Cincinnati - Greenville, SC

  1. What's the distance between Cincinnati and Greenville by coach?

    The journey from Cincinnati to Greenville by coach covers an approximate distance of 319 miles (514 km).

  2. How can I travel from Cincinnati to Greenville avoiding air travel?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/09
US$101
02/09
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Today
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04/09
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05/09
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busbud logoThe cheapest trip from Cincinnati to Greenville, SC was searched and found on 1 Sept 2025 with a price of US$101

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to Greenville, SC as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Cincinnati to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Cincinnati to Greenville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Cincinnati to Greenville.

Tune out to the fine sounds of your best music playlist on your bus trip from Cincinnati to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Cincinnati to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Cincinnati by bus?

Bus from Greenville, SC to Cincinnati

You can also go to Greenville, SC by train

Train from Cincinnati to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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