Bus Tickets from Charleston, SC, US to Knoxville, TN

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Previously seen trips

One passenger / one way

  • Departure time: November 28 at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: November 29 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: December 22 at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: December 23 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: January 11 at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: January 12 at
    Destination city: Knoxville
    Destination location: 100 Kirkwood St
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: July 4 at
    Departure city: Charleston
    Departure location: 4565 Gaynor Ave, North Charleston
    Arrival time: July 5 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:

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Bus Charleston, SC, US to Knoxville, TN: Trip Overview

Average Ticket PriceUS$205
Average Bus Trip Duration1d 7h
Number of daily buses1
Earliest bus departure1:55pm
Distance497 km

Charleston to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Charleston to Knoxville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Charleston to Knoxville.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Charleston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Charleston, SC, US - Knoxville, TN

  1. What is the distance between Charleston and Knoxville?

    The distance between Charleston and Knoxville is approximately 510 km (316 miles).

  2. What are the departure and arrival locations for buses traveling from Charleston to Knoxville?

    Buses departing from Charleston Bus Station in Charleston will take you to 100 Kirkwood St in Knoxville.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Charleston to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Charleston to Knoxville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charleston to Knoxville.

Tune out to the fine sounds of your best music playlist on your bus trip from Charleston to Knoxville while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Charleston, SC, US by bus?

Bus from Knoxville, TN to Charleston, SC, US

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