Bus Tickets from San Luis Obispo to San Francisco, US

Next departures

Next departures for San Luis Obispo to San Francisco on September 19
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
San Luis Obispo
409 Townsend St, SFCheapestFastest
Amtrak
AMTRAK Station
Mission St & Fremont StNo tags
Amtrak
AMTRAK Station
Mission St & Fremont StNo tags
Amtrak
Cal Poly Vista Grande Dining Complex
Mission St & Fremont StNo tags
Amtrak
Cal Poly Vista Grande Dining Complex
Mission St & Fremont StNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Luis Obispo to San Francisco.

Bus
Average Price$39 - $56Average Duration4h 10m
8kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$108 - $108Average Duration7h 40m
29kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Luis Obispo to San Francisco

Among the sustainable travel choices, the bus stands out as the good way to reach San Francisco. The journey takes about 4 hours 10 minutes and with fares starting at just $39, it presents an excellent value for a comfortable ride.

1bus per day
4h 10mAverage Duration
$39Cheapest ticket
8kgCO₂ emissions

Bus San Luis Obispo to San Francisco, US: Trip Overview

Average ticket price$46
Average bus trip duration4h 10m
Number of daily buses1
Earliest bus departure1:30pm
Distance198 miles (319 km)
Latest bus departure3:55pm

San Luis Obispo to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from San Luis Obispo to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Luis Obispo to San Francisco from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from San Luis Obispo to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Luis Obispo - San Francisco, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/16
$84
09/17
$33
Today
$39
09/19
$48
09/20
$37
09/21
$38
09/22
$36
09/23
$42
busbud logoThe cheapest trip from San Luis Obispo to San Francisco, US was searched and found on Sep 17, 2025 with a price of $33

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Francisco, US, as early as possible.

You can expect to pay from $33 to $89 for a bus ticket from San Luis Obispo to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $36 which is on 2025-09-22.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Luis Obispo to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Luis Obispo to San Francisco, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Luis Obispo to San Francisco that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Luis Obispo to San Francisco, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from San Luis Obispo to San Francisco, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Luis Obispo by bus?

Bus from San Francisco, US to San Luis Obispo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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